SCHEMBL442435

SCHEMBL442435

O=C(O)OSc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.43
HPGD P15428 4/20 0.39
MAPT P10636 2/20 0.39
HSD17B10 Q99714 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MGLL Q99685 1/20 0.39
ALDH1A1 P00352 6/20 0.39
LMNA P02545 2/20 0.37
F2 P00734 1/20 0.37
PLIN1 O60240 1/20 0.36
HTT P42858 1/20 0.36
PLIN5 Q00G26 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ABHD5 Q8WTS1 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
TSHR P16473 2/20 0.36
DAO P14920 1/20 0.36
NAPRT Q6XQN6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7091386 0.85 FFAR1 (0.43) FFAR1HPGDMAPTHSD17B10SMN1; SMN2
SCHEMBL28949683 0.82 KMO (0.44) MGLL
SCHEMBL8702557 0.81 ALDH1A1 (0.42) FFAR1HPGDMAPTHSD17B10SMN1; SMN2
SCHEMBL5355354 0.81 ALDH1A1 (0.45) FFAR1HPGDMAPTHSD17B10SMN1; SMN2
SCHEMBL8082139 0.81 SIRT1 (0.42) FFAR1HPGDMAPTHSD17B10SMN1; SMN2
SCHEMBL29561147 0.81 ALDH1A1 (0.41) FFAR1HPGDMAPTHSD17B10SMN1; SMN2
SCHEMBL15361916 0.79 FFAR1 (0.43) FFAR1HPGDSMN1; SMN2ALDH1A1SIRT1
SCHEMBL3062362 0.79 LMNA (0.54) HPGDMAPTHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL9622256 0.79 LMNA (0.48) FFAR1HPGDMAPTHSD17B10SMN1; SMN2
Methyl Alcohol SCHEMBL6766122 0.79 ALDH1A1 (0.44) FFAR1HPGDMAPTHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486771-A Thiocarbonate-based hydrogen sulfide donor, and preparation method and application thereof 上海交通大学 2024-02-02 CN claimed
CN-115850356-A Deoxynucleoside analogue and preparation method thereof 华东理工大学 2023-03-28 CN claimed
CN-115745899-A Mercury (II) fluorescent probe, preparation method and application thereof 郑州师范学院 2023-03-07 CN claimed
CN-113292535-B Method for preparing apaluamide intermediate and apaluamide 南京方生和医药科技有限公司 2022-07-01 CN claimed
CN-114040778-A Cell binding molecule-Tubulysin derivative conjugate and preparation method thereof 杭州多禧生物科技有限公司 2022-02-11 CN claimed
CN-113292535-A Method for preparing apaluamide intermediate and apaluamide 南京方生和医药科技有限公司 2021-08-24 CN claimed
CN-112961087-A Preparation process of high-yield phenyl isothiocyanate derivative 刘科技 2021-06-15 CN claimed
CN-112939833-A High-yield production process of phenyl isothiocyanate derivative 刘科技 2021-06-11 CN claimed
CN-111057047-B Near-infrared fluorescent probe for detecting Cys in brain of depression mouse and synthetic method and application thereof 山东师范大学 2021-02-23 CN claimed
CN-110698322-B Synthesis method of coastal twinborn anthane diterpene Stemarin 浙江大学 2021-01-26 CN claimed
CN-106841132-B Method for detecting concentration of mercury ions in sample 济南大学 2020-09-01 CN claimed
CN-111057047-A Near-infrared fluorescent probe for detecting Cys in brain of depression mouse and synthetic method and application thereof 山东师范大学 2020-04-24 CN claimed
CN-110845379-A Preparation method of phenyl isothiocyanate derivative 刘科技 2020-02-28 CN claimed
CN-110698322-A Synthesis method of coastal twinborn anthane diterpene Stemarin 浙江大学 2020-01-17 CN claimed
US-5241084-A PREPARATION PROCESS OF GINKGOLIDE B FROM GINKGOLIDE C SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 1993-08-31 US claimed
JP-1249797-A None JP disclosed
JP-5255341-A None JP disclosed
US-4622408-A PROTECTIVE GROUP FOR AMINO ACIDS MERCK & CO., INC. (US) 1986-11-11 US disclosed
US-4333868-A Phosphite ester stabilizers CIBA-GEIGY CORPORATION (US) 1982-06-08 US disclosed
US-4132702-A Phenol esters and amides and polymers stabilized therewith CIBA-GEIGY CORPORATION (US) 1979-01-02 US disclosed