SCHEMBL4424431

SCHEMBL4424431

CC(N)C(N)(C(=O)O)C(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
SLC15A1 P46059 2/20 0.48
KMT2A Q03164 3/20 0.45
SLC1A3 P43003 2/20 0.45
SLC1A2 P43004 2/20 0.45
SLC1A1 P43005 2/20 0.45
MEN1 O00255 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CTSK P43235 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
LTA4H P09960 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064496 0.89 ALDH1A1 (0.50) ALDH1A1SLC15A1KMT2ASLC1A3SLC1A2
SCHEMBL6064499 0.89 ALDH1A1 (0.50) ALDH1A1SLC15A1KMT2ASLC1A3SLC1A2
SCHEMBL27711459 0.88 ALDH1A1 (0.49) ALDH1A1SLC15A1KMT2ASLC1A3SLC1A2
SCHEMBL16915235 0.85 SLC1A3 (0.45) ALDH1A1SLC15A1KMT2ASLC1A3SLC1A2
SCHEMBL16915234 0.85 SLC1A3 (0.45) ALDH1A1SLC15A1KMT2ASLC1A3SLC1A2
SCHEMBL30600448 0.84 ALDH1A1 (0.51) ALDH1A1SLC15A1KMT2ASLC1A3SLC1A2
SCHEMBL29462738 0.84 ALDH1A1 (0.47) ALDH1A1SLC15A1KMT2ASLC1A3SLC1A2
SCHEMBL4647195 0.83 ALDH1A1 (0.44) ALDH1A1SLC15A1KMT2ASLC1A3SLC1A2
SCHEMBL28006785 0.82 ALDH1A1 (0.46) ALDH1A1SLC15A1KMT2ASLC1A3SLC1A2
SCHEMBL27780857 0.82 LTA4H (0.44) ALDH1A1SLC15A1KMT2ASLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7541018-B2 Treatment process using somatostatin analogues UNIVERSITY OF BERN (CH) 2009-06-02 US disclosed
US-20070154392-A1 TREATMENT PROCESS USING SOMATOSTATIN ANALOGUES UNIVERSITY HOSPITAL BASEL (CH) 2007-07-05 US disclosed
US-7192570-B2 Compositions of somatostatin analogues UNIVERSITY OF BERN (CH) 2007-03-20 US disclosed
EP-1419178-B1 SOMATOSTATIN ANALOGUES AND THEIR USE SOMATOSTATIN ANALOGUES BINDING TO ALL SOMATOSTATIN RECEPTOR AND THEIR USE UNIV BERN (CH) 2006-05-31 EP disclosed
US-20040242842-A1 Somatostatin analogues and their use somatostatin analogues binding to all somatostatin receptor and their use UNIVERSITY OF BERN (CH) 2004-12-02 US disclosed
EP-1419178-A1 SOMATOSTATIN ANALOGUES AND THEIR USE SOMATOSTATIN ANALOGUES BINDING TO ALL SOMATOSTATIN RECEPTOR AND THEIR USE University of Bern (CH) 2004-05-19 EP disclosed
WO-2003014158-A1 SOMATOSTATIN ANALOGUES AND THEIR USE SOMATOSTATIN ANALOGUES BINDING TO ALL SOMATOSTATIN RECEPTOR AND THEIR USE UNIVERSITY OF BERN (CH) 2003-02-20 WO disclosed
EP-1283216-A1 Somatostatin analogues binding to all somatostatin receptor subtypes and their use Mallinckrodt Inc. (US) 2003-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070154392-A1 TREATMENT PROCESS USING SOMATOSTATIN ANALOGUES NPR1, NPR3, SSTR3 ALDH1A1 4762/4885SLC15A1 458/4885KMT2A 1395/4885
US-20040242842-A1 Somatostatin analogues and their use somatostatin analogues binding to all somatostatin receptor and their use SSTR5, NPY5R, GLP1R ALDH1A1 3997/4885SLC15A1 703/4885KMT2A 1697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.