Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | TAF1 | P21675 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930600 | 0.82 | OPRM1 (0.42) | OPRM1OPRL1 | |
| SCHEMBL1929076 | 0.81 | OPRM1 (0.54) | OPRM1OPRL1 | |
| SCHEMBL1929418 | 0.78 | OPRM1 (0.43) | OPRM1OPRL1 | |
| SCHEMBL8226783 | 0.76 | OPRM1 (0.51) | OPRM1OPRL1 | |
| SCHEMBL4421699 | 0.71 | OPRM1 (0.40) | OPRM1OPRL1 | |
| SCHEMBL8224275 | 0.68 | OPRM1 (0.47) | OPRM1OPRL1 | |
| SCHEMBL27687407 | 0.67 | P2RX7 (0.33) | — | |
| SCHEMBL13380553 | 0.66 | OPRM1 (0.57) | OPRM1OPRL1 | |
| SCHEMBL13380625 | 0.66 | OPRM1 (0.57) | OPRM1OPRL1 | |
| SCHEMBL3412257 | 0.63 | L3MBTL3 (0.33) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035411-A1 | MUSCARINIC RECEPTOR AGONISTS THAT ARE EFFECTIVE IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA. | Astra Zeneca AB (SE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007142583-A1 | MUSCARINIC RECEPTOR AGONISTS THAT ARE EFFECTIVE IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA. | ASTRAZENECA AB (SE) | 2007-12-13 | — | — | WO | disclosed |