SCHEMBL4424912

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18397902	0.85	LOXL2 (0.44)	KDM4ATP53MAPTALDH1A1KDM4E
	SCHEMBL6485858	0.83	TBXAS1 (0.43)	TBXAS1HDAC6TP53MAPTALDH1A1
	SCHEMBL3512251	0.82	KDM4A (0.54)	KDM4ATP53MAPTALDH1A1KDM4E
	SCHEMBL30344871	0.82	ALDH1A1 (0.39)	KDM4AMAPTALDH1A1KDM4EGLA
	SCHEMBL15862351	0.78	EPHX2 (0.51)	HDAC6KDM4AMAPTHDAC1BRD4
	SCHEMBL19079911	0.78	PRMT5 (0.55)	HDAC6KDM4AMAPTALDH1A1KDM4E
	SCHEMBL16790458	0.77	EPHX2 (0.48)	HDAC6KDM4AMAPTHDAC1ACACB
	SCHEMBL25155268	0.76	ALDH1A1 (0.38)	KDM4AMAPTALDH1A1KDM4EGLA
	SCHEMBL30344243	0.76	ALDH1A1 (0.38)	KDM4AMAPTALDH1A1KDM4EGLA
	SCHEMBL2901877	0.76	TBXAS1 (0.47)	TBXAS1HDAC6TP53KDM4EF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.