Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442518 | 0.84 | HIF1A (0.41) | HIF1AALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9013559 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10707090 | 0.73 | NPSR1 (0.43) | ALDH1A1MEN1MAPTKMT2AADORA3 | |
| SCHEMBL11203252 | 0.70 | GAA (0.38) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11765477 | 0.67 | MAPK1 (0.50) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7151799 | 0.67 | — | — | |
| SCHEMBL11203981 | 0.65 | ALDH1A1 (0.40) | HIF1AALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9350181 | 0.64 | ADORA2A (0.43) | ALDH1A1MEN1MAPTKMT2AADORA2A | |
| SCHEMBL31739252 | 0.63 | MAOA (0.61) | MAPTLMNAHTT | |
| SCHEMBL1154450 | 0.62 | NPC1 (0.41) | ALDH1A1MEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102388027-B | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG | 2015-07-01 | — | — | CN | disclosed |
| US-8470739-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENE AG (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8470739-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENE AG (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8470739-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENE AG (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8138211-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-8138211-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-8138211-B2 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| EP-2391612-A1 | Isothiazolyloxyphenyl amidines and use thereof as fungicides | Bayer CropScience AG (DE) | 2011-12-07 | — | — | EP | disclosed |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-02 | — | — | US | disclosed |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-02 | — | — | US | disclosed |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-02 | — | — | US | disclosed |
| EP-2223917-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | Bayer CropScience AG (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-2223917-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | Bayer CropScience AG (DE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2010086118-A1 | ISOTHIAZOLYLOXYPHENYL AMIDINES AND USE THEREOF AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010086118-A1 | ISOTHIAZOLYLOXYPHENYL AMIDINES AND USE THEREOF AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065061-A1 | ISOTHIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES | DDT, CYP3A5, INMT | HIF1A 4399/4885ALDH1A1 526/4885MEN1 784/4885 |
| US-20110130282-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | DDT, CYP3A5, INMT | HIF1A 4399/4885ALDH1A1 526/4885MEN1 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.