SCHEMBL4425839

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15163844	0.89	STIM1 (0.54)	STIM1ORAI1KDM4ESCD5KLKB1
	SCHEMBL4423293	0.88	SCD5 (0.59)	STIM1ORAI1SCD5SCDORAI3
	SCHEMBL15163819	0.84	KDM4E (0.54)	KDM4ESCD5SCDTAS2R8SMN1; SMN2
	SCHEMBL4428896	0.83	SCD5 (0.64)	STIM1ORAI1SCD5SCDORAI3
	SCHEMBL15152902	0.81	STIM1 (0.46)	STIM1ORAI1KDM4ESCD5KLKB1
	SCHEMBL715052	0.79	STIM1 (1.00)	STIM1ORAI1KLKB1ORAI3MEN1
	SCHEMBL30096538	0.79	STIM1 (1.00)	STIM1ORAI1KLKB1ORAI3MEN1
	SCHEMBL2720956	0.77	STIM1 (0.50)	STIM1ORAI1KDM4EKLKB1JAK2
	SCHEMBL4434159	0.77	SCD5 (0.50)	KDM4ESCD5SCDALDH1A1MAPT
	SCHEMBL4434160	0.76	SCD5 (0.61)	KDM4ESCD5SCDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.