SCHEMBL4423293

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4428896	0.89	SCD5 (0.64)	SCD5SCDSTIM1ORAI1ORAI3
	SCHEMBL4425839	0.88	STIM1 (0.65)	SCD5SCDSTIM1ORAI1ORAI3
	SCHEMBL4434159	0.84	SCD5 (0.50)	SCD5SCDHPGD
	SCHEMBL4434160	0.83	SCD5 (0.61)	SCD5SCDHPGD
	SCHEMBL4420874	0.83	SCD5 (0.55)	SCD5SCDHPGD
	SCHEMBL15190572	0.82	SCD5 (0.61)	SCD5SCDCYP2C19HPGD
	SCHEMBL15163844	0.82	STIM1 (0.54)	SCD5SCDSTIM1ORAI1ORAI3
	SCHEMBL4434304	0.80	SCD5 (0.52)	SCD5SCDHPGD
	SCHEMBL4429422	0.80	ALDH1A1 (0.54)	SCD5SCDHPGD
	SCHEMBL760683	0.79	STIM1 (0.78)	STIM1ORAI1ORAI3CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.