Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441900 | 0.86 | KDM4E (0.39) | CA12MEN1KMT2AKDM4EELANE | |
| SCHEMBL2373539 | 0.85 | RBP4 (0.37) | HSD11B1RBP4KCNN4SLC6A7CA12 | |
| SCHEMBL442286 | 0.84 | — | — | |
| SCHEMBL438893 | 0.84 | DPP4 (0.33) | KCNN4CA12CA9PAX8ALDH1A1 | |
| SCHEMBL442116 | 0.83 | MAPT (0.39) | HSD11B1RBP4KCNN4SLC6A7GAA | |
| SCHEMBL441215 | 0.82 | ITGB1 (0.38) | HSD11B1RBP4SLC6A7GAAALDH1A1 | |
| SCHEMBL442117 | 0.76 | RBP4 (0.38) | HSD11B1RBP4SLC6A7GAAALDH1A1 | |
| SCHEMBL441216 | 0.75 | ITGB1 (0.38) | HSD11B1RBP4SLC6A7GAAALDH1A1 | |
| SCHEMBL409566 | 0.73 | METAP2 (0.35) | SLC6A7KMT2AALDH1A1CYP1A2 | |
| SCHEMBL271547 | 0.72 | SCN5A (0.34) | HSD11B1RBP4KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065065-A1 | HERBICIDALLY ACTIVE PYRIDYLKETOSULTAMS | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065065-A1 | HERBICIDALLY ACTIVE PYRIDYLKETOSULTAMS | PDXK, CBR3, CBR1 | HSD11B1 1007/4885RBP4 2759/4885KCNN4 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.