Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432989 | 0.91 | FAAH (0.46) | HDAC8HPGDKDM4ETHRB | |
| SCHEMBL4422197 | 0.76 | NAPRT (0.57) | NAPRTHSD17B10NQO2KLK7MEN1 | |
| SCHEMBL29131182 | 0.76 | HSD17B10 (0.57) | NAPRTHSD17B10NQO2KLK7MEN1 | |
| SCHEMBL4431430 | 0.74 | PTGDR2 (0.42) | HDAC8MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14318446 | 0.73 | ADRB2 (0.45) | HDAC8KMT2AALDH1A1RAB9AADORA3 | |
| SCHEMBL29131166 | 0.72 | HSD17B10 (0.52) | NAPRTHSD17B10NQO2KLK7MEN1 | |
| Hydrogen Sulfide SCHEMBL27704713 | 0.71 | MAPT (0.63) | NAPRTHSD17B10NQO2MEN1KMT2A | |
| SCHEMBL9969534 | 0.71 | SMN1; SMN2 (0.63) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL29131177 | 0.70 | KMT2A (0.57) | NAPRTHSD17B10NQO2MEN1KMT2A | |
| SCHEMBL5149360 | 0.70 | HNF4A (0.50) | HDAC8KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547783-B2 | Transition metal complexes | SHELL OIL COMPANY (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547783-B2 | Transition metal complexes | SHELL OIL COMPANY (US) | 2009-06-16 | — | — | US | disclosed |
| EP-1740598-B1 | TRANSITION METAL COMPLEXES | SHELL INT RESEARCH (NL) | 2008-03-05 | — | — | EP | disclosed |
| EP-1740598-A1 | TRANSITION METAL COMPLEXES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2007-01-10 | — | — | EP | disclosed |
| US-20050215792-A1 | Transition metal complexes | SHELL OIL COMPANY | 2005-09-29 | — | — | US | disclosed |
| WO-2005090371-A1 | TRANSITION METAL COMPLEXES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215792-A1 | Transition metal complexes | NCLN, PRNP, PARN | NAPRT 968/4885HSD17B10 3822/4885HDAC8 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.