Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 7/20 | 0.42 |
| ▸ | CMA1 | P23946 | 2/20 | 0.41 |
| ▸ | TACR3 | P29371 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 5/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427172 | 0.93 | CASP1 (0.43) | CASP1CMA1TACR3IDH1FPR1 | |
| SCHEMBL4437254 | 0.90 | FPR1 (0.36) | CASP1CMA1FPR1FPR2CTSA | |
| SCHEMBL4426944 | 0.88 | FPR1 (0.39) | CASP1FPR1FPR2CTSA | |
| SCHEMBL4427187 | 0.88 | MMP2 (0.38) | CASP1FPR1CTSA | |
| SCHEMBL7429087 | 0.88 | MMP2 (0.38) | CASP1FPR1CTSA | |
| SCHEMBL4426794 | 0.88 | CASP1 (0.39) | CASP1TACR3FPR1CTSA | |
| SCHEMBL6763118 | 0.85 | CTSA (0.40) | FPR1FPR2CTSA | |
| SCHEMBL4435400 | 0.85 | CTSA (0.40) | FPR1CTSA | |
| SCHEMBL8506622 | 0.85 | CTSA (0.40) | FPR1CTSA | |
| SCHEMBL4435399 | 0.85 | CTSA (0.40) | FPR1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |