Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30776799 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| Hydrochloric Acid SCHEMBL8534995 | 0.98 | ALDH1A1 (0.37) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| Hydrochloric Acid SCHEMBL8537064 | 0.98 | ALDH1A1 (0.37) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| SCHEMBL9489660 | 0.87 | POLB (0.44) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| Anisole SCHEMBL11145281 | 0.84 | CA4 (0.45) | ALDH1A1CYP3A4TDP1MAPK1TUBB4A | |
| SCHEMBL18719355 | 0.84 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| SCHEMBL27967338 | 0.84 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| SCHEMBL3005373 | 0.84 | CYP3A4 (0.40) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| SCHEMBL8034663 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| SCHEMBL5177958 | 0.80 | ACHE (0.40) | ALDH1A1CYP3A4TSHRTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465552-B2 | Thickened hair colors | ISP INVESTMENTS, INC. (US) | 2013-06-18 | — | — | US | claimed |
| US-20120317734-A1 | THICKENED HAIR COLORS | ISP INVESTMENTS INC. (US) | 2012-12-20 | — | — | US | claimed |
| EP-0459900-B2 | Process for dyeing of keratinic fibres with 2,4-diamino-1,3-dimethoxybenzene in an acid medium and composition using this process | OREAL (FR) | 2002-08-28 | — | — | EP | claimed |
| EP-0853471-B1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES, AND DYEING METHOD USING SAME | OREAL (FR) | 2001-10-31 | — | — | EP | claimed |
| WO-1999066889-A1 | NEW COUPLING COMPONENTS FOR OXIDATION HAIR COLOURING PRODUCTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-12-29 | — | — | WO | claimed |
| US-6004356-A | HAIR DYES | L'OREAL (FR) | 1999-12-21 | — | — | US | claimed |
| US-5938792-A | APPLYING TO KERATINOUS FIBERS UNDER BASIC CONDITIONS COMPOSITION COMPRISING AMINOINDOLE COUPLER, OXIDATION DYE PRECURSOR, OXIDIZING AGENT | L'OREAL (FR) | 1999-08-17 | — | — | US | claimed |
| US-5900028-A | Oxidation dye composition for keratin fibres comprising 2-amino-3-hydroxypyridine and a P-phenylenediamine or P-aminophenol oxidation base, and dyeing process | L 'OREAL (FR) | 1999-05-04 | — | — | US | claimed |
| EP-0663814-B1 | PROCESS FOR DYEING KERATIN FIBRES USING AN ACID PH ALCOXYMETEPHENYLENEDIAMINE AND COMPOSITIONS THEREFOR | OREAL (FR) | 1999-04-28 | — | — | EP | claimed |
| EP-0630642-B1 | Naphthol couplers | BRISTOL MYERS SQUIBB CO (US) | 1998-08-12 | — | — | EP | claimed |
| US-4891045-A | DYEING HAIR | L'OREAL (FR) | 1990-01-02 | — | — | US | claimed |
| US-4865619-A | Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler | L'OREAL (FR) | 1989-09-12 | — | — | US | claimed |
| US-4865618-A | New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said | L'OREAL (FR) | 1989-09-12 | — | — | US | claimed |
| US-4865617-A | Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers | L'OREAL (FR) | 1989-09-12 | — | — | US | claimed |
| EP-0295474-A1 | Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions | L'OREAL (FR) | 1988-12-21 | — | — | EP | claimed |
| EP-0294669-A1 | Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair | L'OREAL (FR) | 1988-12-14 | — | — | EP | claimed |
| US-4692166-A | OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE | L'OREAL (FR) | 1987-09-08 | — | — | US | claimed |
| US-4563188-A | SHADES OF GREEN | L'OREAL (FR) | 1986-01-07 | — | — | US | claimed |
| US-4324553-A | OXIDATION COLOR DYES | L'OREAL (FR) | 1982-04-13 | — | — | US | claimed |
| US-4323360-A | Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent | L'OREAL (FR) | 1982-04-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120317734-A1 | THICKENED HAIR COLORS | KRT18, PLOD3, PLOD1 | ALDH1A1 1954/4885CYP3A4 1106/4885TSHR 3482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.