Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 18/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 16/20 | 0.66 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1932531 | 0.93 | PGR (0.57) | PGRNR3C1NR3C2 | |
| SCHEMBL1931765 | 0.91 | PGR (0.68) | PGRNR3C1NR3C2MAPTHSD17B10 | |
| SCHEMBL4430304 | 0.90 | PGR (0.70) | PGRNR3C1NR3C2MAPT | |
| SCHEMBL4940061 | 0.89 | PGR (0.62) | PGRNR3C1NR3C2MAPT | |
| SCHEMBL4437182 | 0.89 | PGR (0.71) | PGRNR3C1NR3C2 | |
| SCHEMBL1932392 | 0.88 | PGR (0.61) | PGRNR3C1NR3C2MAPTHSD17B10 | |
| SCHEMBL1932147 | 0.87 | PGR (0.71) | PGRNR3C1NR3C2MAPT | |
| SCHEMBL4427973 | 0.86 | PGR (0.53) | PGRNR3C1NR3C2MAPTHSD17B10 | |
| SCHEMBL1932719 | 0.85 | PGR (0.69) | PGRNR3C1NR3C2MAPTIMPDH2 | |
| SCHEMBL1932378 | 0.85 | PGR (0.70) | PGRNR3C1NR3C2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121670-A2 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | Bausch & Lomb Incorporated (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008088969-A2 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | BAUSCH & LOMB INCORPORATED (US) | 2008-07-24 | — | — | WO | disclosed |
| US-20080171873-A1 | Synthesis of selected stereoisomers of certain substituted alcohols | BAUSCH & LOMB INCORPORATED | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171873-A1 | Synthesis of selected stereoisomers of certain substituted alcohols | ADH1A, ADH1C, ADH5 | PGR 3574/4885NR3C1 74/4885NR3C2 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.