SCHEMBL211511

SCHEMBL211511

C=C(C)C(=O)OCCN1C(=O)C=CC1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 5/20 0.48
THRB P10828 1/20 0.44
TSHR P16473 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
BLM P54132 1/20 0.43
WRN Q14191 1/20 0.43
HIF1A Q16665 1/20 0.43
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
FAAH O00519 3/20 0.41
HTT P42858 2/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HSP90AA1 P07900 1/20 0.39
TLR9 Q9NR96 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14764411 0.90 TSHR (0.49) MGLLTHRBTSHRALDH1A1HPGD
SCHEMBL17767404 0.87 MGLL (0.38) MGLLTHRBTSHRALDH1A1HPGD
SCHEMBL8747653 0.84 ALDH1A1 (0.56) MGLLTHRBTSHRALDH1A1HPGD
SCHEMBL17767388 0.82 OPRM1 (0.42) MGLLTHRBTSHRALDH1A1HPGD
SCHEMBL3173590 0.82 MGLL (0.55) MGLLALDH1A1HPGDCYP1A2CYP2C19
SCHEMBL1077589 0.79 ALDH1A1 (0.46) THRBTSHRALDH1A1HTTPOLB
SCHEMBL2036447 0.79 THRB (0.44) THRBTSHRALDH1A1HPGDHTT
SCHEMBL12603529 0.78 THRB (0.43) THRBTSHRALDH1A1HTTPOLB
SCHEMBL31556453 0.78 THRB (0.43) THRBTSHRHTTPOLBAPEX1
SCHEMBL29631612 0.78 SMN1; SMN2 (0.60) TSHRALDH1A1HPGDPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3221698-B1 POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF Global Life Sciences Solutions Operations UK Ltd (GB) 2021-02-17 EP claimed
WO-2023190309-A1 SURFACE-MODIFIER RESIN COMPOSITION 住友ベークライト株式会社 2023-10-05 WO disclosed
US-11767431-B2 Coloring composition, method for producing coloring composition, color filter, pattern forming method, solid-state imaging device, and image display device FUJIFILM CORPORATION (JP) 2023-09-26 US disclosed
US-11754563-B2 Porous membranes with a polymer grafting, methods and uses thereof Global Life Sciences Solutions Operations UK Ltd (GB) 2023-09-12 US disclosed
US-11754563-B2 Porous membranes with a polymer grafting, methods and uses thereof Global Life Sciences Solutions Operations UK Ltd (GB) 2023-09-12 US disclosed
WO-2023013687-A1 ANTIBACTERIAL/ANTIVIRAL AGENT COMPOSITION, ANTIBACTERIAL/ANTIVIRAL STRUCTURE, AND ANTIBACTERIAL/ANTIVIRAL STRUCTURE PRODUCTION METHOD 日華化学株式会社 2023-02-09 WO disclosed
CN-107077067-B Photosensitive resin composition, photosensitive resin laminate, method for producing resin pattern, cured film, and display device 旭化成株式会社 2021-04-13 CN disclosed
CN-107003306-B Porous membranes with polymer grafts, methods and uses thereof 通用电气公司 2020-07-03 CN disclosed
CN-105122137-B Photosensitive resin composition, protective film or insulating film, touch panel, and method for producing same 东丽株式会社 2020-02-07 CN disclosed
US-10338468-B2 Photosensitive resin composition, photosensitive resin laminate, resin pattern production method, cured film, and display device ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-07-02 US disclosed
US-6139146-A Programmable corrective lenses NOVARTIS AG (CH) 2000-10-31 US disclosed
EP-1044389-A2 ACTIVELY CONTROLLABLE MULTIFOCAL LENS Novartis AG (CH) 2000-10-18 EP disclosed
EP-1044390-A1 PROGRAMMABLE CORRECTIVE LENS Novartis AG (CH) 2000-10-18 EP disclosed
US-5997140-A Actively controllable multifocal lens NOVARTIS AG (CH) 1999-12-07 US disclosed
US-5936052-A Cross-linkable copolymers and hydrogels CIBA VISION CORPORATION (US) 1999-08-10 US disclosed
WO-1999034244-A1 PROGRAMMABLE CORRECTIVE LENS NOVARTIS AG (CH) 1999-07-08 WO disclosed
WO-1999034239-A2 ACTIVELY CONTROLLABLE MULTIFOCAL LENS NOVARTIS AG (CH) 1999-07-08 WO disclosed
EP-0655470-B1 Cross-linkable copolymers and hydrogels NOVARTIS AG (CH) 1999-05-12 EP disclosed
US-5712356-A Cross-linkable copolymers and hydrogels CIBA VISION CORPORATION (US) 1998-01-27 US disclosed
EP-0655470-A1 Cross-linkable copolymers and hydrogels CIBA-GEIGY AG (CH) 1995-05-31 EP disclosed