SCHEMBL4428252

SCHEMBL4428252

CCO[Si](CC(O)CO)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
USP2 O75604 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7110217 0.79 LMNA (0.35) LMNA
SCHEMBL28127990 0.78 ALDH1A1 (0.31) LMNAALDH1A1
SCHEMBL28127903 0.77 THRB (0.39) LMNAALDH1A1USP2THRB
SCHEMBL28113100 0.77 ALDH1A1 (0.33) LMNAALDH1A1USP2
SCHEMBL329143 0.75 TSHR (0.38) LMNAALDH1A1THRB
SCHEMBL4431770 0.75 LMNA (0.40) LMNAALDH1A1USP2THRB
Alcohol SCHEMBL28068444 0.73 TSHR (0.32) ALDH1A1
SCHEMBL6284646 0.71 THRB (0.33) LMNATHRB
Glycerin SCHEMBL28131814 0.71 ALDH1A1 (0.33) LMNAALDH1A1USP2
SCHEMBL22442017 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190227060-A1 MICROARRAY HAVING A BASE CLEAVABLE LINKER CUSTOMARRAY, INC. (US) 2019-07-25 US disclosed
US-10261075-B2 Microarray having a base cleavable linker CUSTOMARRAY, INC. (US) 2019-04-16 US disclosed
US-20180267032-A1 Microarray Having a Base Cleavable Linker CUSTOMARRAY, INC. (US) 2018-09-20 US disclosed
US-9983204-B2 Microarray having a base cleavable linker CUSTOMARRAY, INC. (US) 2018-05-29 US disclosed
CN-104212409-B The main binding agent being made up of polyorganosiloxane compounds 琳得科株式会社 2016-08-24 CN disclosed
US-20090280998-A1 Microarray having a base cleavable linker CUSTOMARRAY, INC. 2009-11-12 US disclosed
US-7541314-B2 Microarray having a base cleavable sulfonyl linker COMBIMATRIX CORPORATION (US) 2009-06-02 US disclosed
WO-2007100793-A2 MICROARRAY HAVING A BASE CLEAVABLE SULFONYL LINKER COMBIMATRIX CORPORATION (US) 2007-09-07 WO disclosed
US-20070202509-A1 Microarray having a base cleavable sulfonyl linker COMBIMATRIX CORPORATION 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070202509-A1 Microarray having a base cleavable sulfonyl linker DPP8, DPP4, SI LMNA 2543/4885ALDH1A1 2720/4885USP2 1454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.