SCHEMBL4428525

SCHEMBL4428525

C[N+]1(C)CCNC1c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.38
ADRA1A P35348 2/20 0.38
SLC6A3 Q01959 2/20 0.38
HTR2B P41595 1/20 0.38
GID4 Q8IVV7 1/20 0.38
SLC18A3 Q16572 2/20 0.36
SIGMAR1 Q99720 1/20 0.36
MAOA P21397 9/20 0.35
MAOB P27338 9/20 0.35
KDM1A O60341 7/20 0.35
PRCP P42785 1/20 0.35
CYP2C19 P33261 4/20 0.34
CYP2B6 P20813 3/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP2C9 P11712 2/20 0.34
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25232904 0.80 CHRNB2 (0.54) CYP2C19CYP1A2CYP2D6CYP2C9LMNA
SCHEMBL2311507 0.71 CHRNA7 (0.33) SLC6A2ADRA1ASLC6A3HTR2BSLC18A3
SCHEMBL2656101 0.71 ALDH1A1 (0.38) SLC6A2SLC6A3CYP2C19CYP1A2HTR2C
Hydrochloric Acid SCHEMBL6830548 0.68 SLC18A3 (0.37) SLC18A3SIGMAR1MAOAMAOBKDM1A
Iodide SCHEMBL11457678 0.68 SLC18A3 (0.37) SLC18A3SIGMAR1MAOAMAOBKDM1A
SCHEMBL16226181 0.63 TSHR (0.37) SLC6A2ADRA1ASLC6A3SLC18A3MAOA
SCHEMBL8222209 0.61 SLC18A3 (0.52) SLC6A2ADRA1ASLC6A3HTR2BSLC18A3
SCHEMBL1435756 0.61 SLC18A3 (0.46) SLC6A2ADRA1ASLC6A3HTR2BSLC18A3
SCHEMBL6684605 0.61 GBA1 (0.37) SLC6A2ADRA1ASLC6A3HTR2BSLC18A3
SCHEMBL9370820 0.60 CHRM2 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2114899-A2 CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES Firmenich S.A. (CH) 2009-11-11 EP disclosed
WO-2008093272-A2 CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES FIRMENICH SA (CH) 2008-08-07 WO disclosed