Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2547716 | 0.86 | CES2 (0.47) | CES2CES1KEAP1ALOX5CHRM3 | |
| SCHEMBL2821064 | 0.82 | HPGD (0.45) | CES2CES1KEAP1ALOX5CHRM3 | |
| SCHEMBL2547719 | 0.79 | ALOX5 (0.42) | CES2CES1KEAP1ALOX5CHRM3 | |
| SCHEMBL10478379 | 0.78 | CES2 (0.41) | CES2CES1KEAP1ALOX5CHRM3 | |
| SCHEMBL72374 | 0.77 | CES2 (0.50) | CES2CES1KEAP1ALOX5CHRM3 | |
| SCHEMBL72373 | 0.77 | CES2 (0.50) | CES2CES1KEAP1ALOX5CHRM3 | |
| SCHEMBL28627758 | 0.75 | ALDH1A1 (0.47) | CHRM3CHRM2CHRM1CYP2C19ALDH1A1 | |
| Fluoride SCHEMBL14774852 | 0.75 | CES2 (0.48) | CES2CES1KEAP1ALOX5CHRM3 | |
| SCHEMBL7723137 | 0.75 | CES2 (0.48) | CES2CES1KEAP1ALOX5CHRM3 | |
| Fluoride SCHEMBL14931714 | 0.75 | CES2 (0.48) | CES2CES1KEAP1ALOX5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432781-A1 | SALTS OF TIOTROPIUM WITH 10-CAMPHORSULFONIC ACID | Adamed SP. Z O.O. (PL) | 2012-03-28 | — | — | EP | claimed |
| US-20120065226-A1 | SALTS OF TIOTROPIUM WITH 10-CAMPHORSULFONIC ACID | ADAMED SP Z O.O. (PL) | 2012-03-15 | — | — | US | claimed |
| WO-2010133457-A1 | SALTS OF TIOTROPIUM WITH 10-CAMPHORSULFONIC ACID | ADAMED SP. Z O.O. (PL) | 2010-11-25 | — | — | WO | claimed |
| EP-2592078-A1 | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities | Almirall, S.A. (ES) | 2013-05-15 | — | — | EP | disclosed |
| EP-2592077-A1 | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities | Almirall, S.A. (ES) | 2013-05-15 | — | — | EP | disclosed |
| EP-2432781-A1 | SALTS OF TIOTROPIUM WITH 10-CAMPHORSULFONIC ACID | Adamed SP. Z O.O. (PL) | 2012-03-28 | — | — | EP | disclosed |
| US-20120065226-A1 | SALTS OF TIOTROPIUM WITH 10-CAMPHORSULFONIC ACID | ADAMED SP Z O.O. (PL) | 2012-03-15 | — | — | US | disclosed |
| WO-2010133457-A1 | SALTS OF TIOTROPIUM WITH 10-CAMPHORSULFONIC ACID | ADAMED SP. Z O.O. (PL) | 2010-11-25 | — | — | WO | disclosed |
| WO-2008104955-A1 | AZONIATRICYCLO [3.3.1.0] NONANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065226-A1 | SALTS OF TIOTROPIUM WITH 10-CAMPHORSULFONIC ACID | PDE10A, PDE6A, PDE6H | CES2 3999/4885CES1 1527/4885KEAP1 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.