Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 9/20 | 0.77 |
| ▸ | DHFR | P00374 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | ALB | P02768 | 1/20 | 0.61 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.60 |
| ▸ | HNF4A | P41235 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412439 | 0.87 | ACMSD (1.00) | ACMSDDHFRKDM4EMEN1USP2 | |
| SCHEMBL17202660 | 0.81 | MCL1 (0.77) | ACMSDDHFRKDM4EMEN1USP2 | |
| SCHEMBL444743 | 0.79 | ACMSD (0.62) | ACMSDDHFRKDM4EMEN1USP2 | |
| SCHEMBL2533617 | 0.78 | ACMSD (0.76) | ACMSDDHFRKDM4EMEN1USP2 | |
| SCHEMBL11014667 | 0.77 | ACMSD (0.47) | ACMSDDHFRKDM4EMEN1USP2 | |
| SCHEMBL3992448 | 0.76 | KDM4E (0.68) | ACMSDDHFRKDM4EMEN1USP2 | |
| Diflunisal SCHEMBL4337 | 0.76 | ACMSD (1.00) | ACMSDDHFRKDM4EMEN1USP2 | |
| Diflunisal SCHEMBL30509654 | 0.76 | ACMSD (1.00) | ACMSDDHFRKDM4EMEN1USP2 | |
| Diflunisal SCHEMBL29367380 | 0.76 | ACMSD (1.00) | ACMSDDHFRKDM4EMEN1USP2 | |
| Diflunisal SCHEMBL3848363 | 0.76 | ACMSD (1.00) | ACMSDDHFRKDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103864606-A | Eutectic of diflunisal and pyridine formamide compounds and preparation method thereof | SUZHOU INST NANO TECH & NANO B | 2014-06-18 | — | — | CN | disclosed |
| EP-2114384-A2 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSMUCOSAL DELIVERY | Derma-Young Ltd. (IL) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008099397-A2 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSMUCOSAL DELIVERY | DERMA-YOUNG LTD. (IL) | 2008-08-21 | — | — | WO | disclosed |
| EP-1893203-A2 | MEDICAMENT CONTAINING A BETAMIMETIC IN CONJUNCTION WITH AN ANTICHOLINERGIC AND A PDE IV INHIBITOR | Boehringer Ingelheim International GmbH (DE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006128847-A2 | MEDICAMENT CONTAINING A BETAMIMETIC IN CONJUNCTION WITH AN ANTICHOLINERGIC AND A PDE IV INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-07 | — | — | WO | disclosed |