Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 10/20 | 0.76 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.76 |
| ▸ | HNF4A | P41235 | 3/20 | 0.76 |
| ▸ | DHFR | P00374 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17202660 | 0.96 | MCL1 (0.77) | ACMSDMCL1HNF4ADHFRKDM4E | |
| SCHEMBL330602 | 0.86 | ACMSD (1.00) | ACMSDMCL1HNF4ADHFRLCK | |
| SCHEMBL23143193 | 0.86 | ACMSD (1.00) | ACMSDMCL1HNF4ADHFRLCK | |
| SCHEMBL9273036 | 0.86 | ACMSD (1.00) | ACMSDMCL1HNF4ADHFRLCK | |
| SCHEMBL29759663 | 0.86 | ACMSD (1.00) | ACMSDMCL1HNF4ADHFRLCK | |
| SCHEMBL28515959 | 0.85 | PTPN1 (0.55) | ACMSDMCL1HNF4ADHFRALDH1A1 | |
| SCHEMBL9652822 | 0.85 | ACMSD (0.96) | ACMSDMCL1HNF4ADHFRLCK | |
| SCHEMBL4260330 | 0.84 | MCL1 (1.00) | ACMSDMCL1HNF4ADHFRKDM4E | |
| SCHEMBL412439 | 0.84 | ACMSD (1.00) | ACMSDMCL1HNF4ADHFRKDM4E | |
| SCHEMBL2557486 | 0.83 | MCL1 (0.69) | ACMSDMCL1HNF4ADHFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394980-B1 | AROMATIC AMINO COMPOUND MANUFACTURING METHOD | HODOGAYA CHEMICAL CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| US-9238624-B2 | Method of producing aromatic amino compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 2016-01-19 | — | — | US | disclosed |
| US-20140163232-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-06-12 | — | — | US | disclosed |
| US-8735626-B2 | Method of producing aromatic amino compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-27 | — | — | US | disclosed |
| EP-2394980-A1 | AROMATIC AMINO COMPOUND MANUFACTURING METHOD | Hodogaya Chemical Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110257404-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | HODOGAYA CHEMICAL CO., LTD. (JP) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163232-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | DDC, AOC2, AOC3 | ACMSD 43/4885MCL1 3218/4885HNF4A 2672/4885 |
| US-20110257404-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | AOC2, AOC3, DDC | ACMSD 63/4885MCL1 2994/4885HNF4A 3115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.