Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427097 | 0.87 | SLC5A2 (0.41) | ALDH1A1LTA4HCA2 | |
| SCHEMBL3672322 | 0.85 | LMNA (0.31) | — | |
| SCHEMBL12535871 | 0.85 | IDO1 (0.44) | — | |
| SCHEMBL727474 | 0.74 | CYP1A1 (0.35) | ALDH1A1 | |
| SCHEMBL17265633 | 0.74 | TSHR (0.37) | ALDH1A1TSHRTDP1MAPK1CA2 | |
| SCHEMBL19315862 | 0.73 | — | — | |
| SCHEMBL1553584 | 0.71 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL27884 | 0.58 | LTA4H (0.81) | ALDH1A1CYP3A4TSHRLTA4HCA2 | |
| SCHEMBL11310162 | 0.58 | ESR1 (0.48) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| SCHEMBL8020885 | 0.58 | ESR1 (0.48) | ALDH1A1CYP3A4TSHRTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442005-B1 | NOVEL DIFUNCTIONAL PHOTOINITIATORS | CIBA HOLDING INC (CH) | 2009-03-18 | — | — | EP | disclosed |
| US-7084183-B2 | Difunctional photoinitiators | CIBA SPECIALTY CHEMCIALS CORP. (US) | 2006-08-01 | — | — | US | disclosed |
| US-20050004249-A1 | Novel disfunctional photoinitiators | IGM GROUP B.V. (NL) | 2005-01-06 | — | — | US | disclosed |
| EP-1442005-A2 | NOVEL DIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003040076-A2 | NOVEL DIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004249-A1 | Novel disfunctional photoinitiators | ETFA, ETFB, PAH | ALDH1A1 7/4885CYP3A4 72/4885TSHR 4191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.