Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | FABP1 | P07148 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830844 | 0.88 | DCTPP1 (0.33) | NAMPTCYP2C9FABP1HTR6 | |
| SCHEMBL1580944 | 0.86 | DCTPP1 (0.34) | GRM4 | |
| SCHEMBL1580761 | 0.85 | SLC40A1 (0.36) | KDM4E | |
| Hydrochloric Acid SCHEMBL2412383 | 0.85 | DCTPP1 (0.33) | GRM4 | |
| SCHEMBL1580308 | 0.85 | HTR6 (0.41) | NAMPTCYP2C9HTR6 | |
| Hydrochloric Acid SCHEMBL2415530 | 0.85 | SLC40A1 (0.36) | KDM4E | |
| SCHEMBL1580925 | 0.84 | L3MBTL1 (0.33) | MAOAMAOBHTR6 | |
| SCHEMBL1580719 | 0.83 | RXFP1 (0.31) | HTR6 | |
| Fumaric Acid SCHEMBL1830756 | 0.83 | DCTPP1 (0.33) | DHODHNAMPTCYP2C9GRM4 | |
| Fumaric Acid SCHEMBL1830751 | 0.83 | DCTPP1 (0.33) | DHODHNAMPTCYP2C9GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |