Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.59 |
| ▸ | VHL | P40337 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429879 | 1.00 | OPRM1 (0.59) | OPRM1VHLFOLH1NAALAD2ITGB1 | |
| SCHEMBL4432469 | 0.91 | VHL (0.58) | OPRM1VHL | |
| SCHEMBL4432474 | 0.91 | VHL (0.58) | OPRM1VHL | |
| SCHEMBL29871823 | 0.83 | OPRM1 (0.54) | OPRM1VHLITGB1ITGA4 | |
| SCHEMBL31114531 | 0.82 | OPRM1 (0.62) | OPRM1OPRD1 | |
| SCHEMBL31059337 | 0.81 | SLC6A2 (0.59) | OPRM1VHLITGB1ITGA4OPRD1 | |
| SCHEMBL30612367 | 0.80 | OPRM1 (0.62) | OPRM1OPRD1 | |
| SCHEMBL4434719 | 0.79 | ATM (0.55) | VHL | |
| SCHEMBL4434711 | 0.79 | ATM (0.55) | VHL | |
| SCHEMBL27687419 | 0.79 | ALDH1A1 (0.53) | OPRM1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117536-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | Beiersdorf AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101693-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | BEIERSDORF AG (DE) | 2008-08-28 | — | — | WO | disclosed |