Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432474 | 1.00 | VHL (0.58) | VHLOPRM1ACELMNATDP1 | |
| SCHEMBL4429873 | 0.91 | OPRM1 (0.59) | VHLOPRM1 | |
| SCHEMBL4429879 | 0.91 | OPRM1 (0.59) | VHLOPRM1 | |
| SCHEMBL4440562 | 0.81 | ALOX15 (0.61) | ACEKMT2A | |
| SCHEMBL4440559 | 0.81 | ALOX15 (0.61) | ACEKMT2A | |
| SCHEMBL4434719 | 0.81 | ATM (0.55) | VHL | |
| SCHEMBL4434711 | 0.81 | ATM (0.55) | VHL | |
| SCHEMBL31256510 | 0.80 | OPRM1 (0.53) | VHLOPRM1ACE | |
| SCHEMBL4432439 | 0.80 | ATM (0.54) | VHL | |
| SCHEMBL4439286 | 0.80 | ATM (0.54) | VHLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117536-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | Beiersdorf AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101693-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | BEIERSDORF AG (DE) | 2008-08-28 | — | — | WO | disclosed |