Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.36 |
| ▸ | FPR1 | P21462 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 8/20 | 0.32 |
| ▸ | MMP3 | P08254 | 3/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429087 | 0.90 | MMP2 (0.38) | CASP1FPR1CTSAMMP2MMP3 | |
| SCHEMBL4427187 | 0.90 | MMP2 (0.38) | CASP1FPR1CTSAMMP2MMP3 | |
| SCHEMBL4424644 | 0.90 | FPR1 (0.37) | CASP1FPR1CTSACYP26A1OPRK1 | |
| SCHEMBL4429149 | 0.90 | CYP26A1 (0.39) | CASP1FPR1CTSACYP26A1 | |
| SCHEMBL4429239 | 0.89 | CASP1 (0.38) | CASP1FPR1CTSAMMP2MMP3 | |
| SCHEMBL7431479 | 0.89 | CASP1 (0.38) | CASP1FPR1CTSAMMP2MMP3 | |
| SCHEMBL4435231 | 0.89 | CASP1 (0.38) | CASP1FPR1CTSAMMP2MMP3 | |
| SCHEMBL4434286 | 0.88 | CTSA (0.39) | FPR1CTSAOPRK1MMP2MMP3 | |
| SCHEMBL4435606 | 0.88 | FPR1 (0.36) | CASP1FPR1CTSACYP26A1OPRK1 | |
| SCHEMBL4435400 | 0.87 | CTSA (0.40) | FPR1CTSACYP26A1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1213288-A1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-06-12 | — | — | EP | disclosed |