Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 3/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGB8 | P26012 | 2/20 | 0.36 |
| ▸ | FPR1 | P21462 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | MMP3 | P08254 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429087 | 0.90 | MMP2 (0.38) | CTSAFPR1MMP2MMP3POLB | |
| SCHEMBL4427187 | 0.90 | MMP2 (0.38) | CTSAFPR1MMP2MMP3POLB | |
| SCHEMBL4427933 | 0.90 | ITGB3 (0.42) | WDR5ITGAVITGB5ITGB6ITGB3 | |
| SCHEMBL4424644 | 0.90 | FPR1 (0.37) | CTSAFPR1MMP2MMP3POLB | |
| SCHEMBL4429149 | 0.90 | CYP26A1 (0.39) | CTSAITGAVITGB5ITGB6ITGB3 | |
| SCHEMBL4435231 | 0.89 | CASP1 (0.38) | CTSAFPR1MMP2MMP3 | |
| SCHEMBL7431479 | 0.89 | CASP1 (0.38) | CTSAFPR1MMP2MMP3 | |
| SCHEMBL4429239 | 0.89 | CASP1 (0.38) | CTSAFPR1MMP2MMP3 | |
| SCHEMBL4429980 | 0.88 | CASP1 (0.36) | CTSAFPR1MMP2MMP3OPRK1 | |
| SCHEMBL4435606 | 0.88 | FPR1 (0.36) | CTSAFPR1MMP2MMP3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1213288-A1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-06-12 | — | — | EP | disclosed |