Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 6/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430101 | 0.84 | HSD17B3 (0.62) | HSD17B3ALPIKDM4EALDH1A1GLA | |
| SCHEMBL1133508 | 0.74 | HSD17B3 (1.00) | HSD17B3ALPIPDE2AMAOAMAOB | |
| SCHEMBL23051357 | 0.73 | MIF (0.55) | HSD17B3KDM4EALDH1A1GLAGAA | |
| SCHEMBL3306142 | 0.69 | HSD17B3 (0.64) | HSD17B3KDM4EALDH1A1GLAGAA | |
| SCHEMBL11879798 | 0.68 | ALDH1A1 (0.59) | HSD17B3KDM4EALDH1A1GLAGAA | |
| SCHEMBL4633658 | 0.67 | TSHR (0.41) | ALDH1A1MAPTCA9NPSR1 | |
| SCHEMBL11874784 | 0.66 | HSD17B3 (0.65) | HSD17B3KDM4EALDH1A1GLAGAA | |
| SCHEMBL6276869 | 0.65 | NQO1 (0.57) | HSD17B3KDM4EALDH1A1GLAGAA | |
| SCHEMBL27817043 | 0.64 | HSD17B3 (0.65) | HSD17B3KDM4EALDH1A1GLAGAA | |
| SCHEMBL15842860 | 0.64 | MAOB (0.72) | HSD17B3ALPIKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134858-A1 | METHODS OF DETERMINING TOTAL PON1 LEVEL | Yeda Research And Development Company Limited (IL) | 2009-12-23 | — | — | EP | claimed |
| WO-2008111062-A1 | METHODS OF DETERMINING TOTAL PON1 LEVEL | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-09-18 | — | — | WO | claimed |