Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.39 |
| ▸ | LGMN | Q99538 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193540 | 0.81 | PDE4A (0.44) | LGMNADORA2APDE4AADORA2BPDE4B | |
| SCHEMBL3794609 | 0.79 | POLB (0.56) | LGMNPOLBPABPC1ATAD2KDM4E | |
| SCHEMBL3012870 | 0.77 | PDE1A (0.48) | PDE3BPDE3AADORA2AADORA1PDE4A | |
| SCHEMBL11178750 | 0.72 | HTT (0.35) | ADORA2APDE4AADORA2BPDE4BPDE4C | |
| SCHEMBL26602092 | 0.72 | ALDH1A1 (0.39) | KDM4EALDH1A1HTTKMT2A | |
| SCHEMBL11175917 | 0.71 | PDE1A (0.35) | PDE3BPDE3AADORA2AADORA1PDE4A | |
| SCHEMBL4724453 | 0.70 | RXFP1 (0.38) | KDM4ERXFP1ALPLALDH1A1HTT | |
| SCHEMBL11175925 | 0.70 | PDE4A (0.34) | ADORA2APDE4AADORA2BPDE4BPDE4C | |
| SCHEMBL612453 | 0.69 | ATAD2 (0.44) | ATAD2KDM4EADORA3ADORA2AADORA1 | |
| SCHEMBL13075951 | 0.67 | ALDH1A1 (0.40) | POLBPABPC1ATAD2ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158719-A2 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| WO-2009158719-A2 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| US-6133273-A | DISORDERS ASSOCIATED WITH BONE LOSS BY INCREASED TRANSCRIPTION AND ELEVATION OF PLASMA CALCITONIN LEVELS INCLUDING PAGET'S DISEASE, POST MENOPAUSAL OSTEOPOROSIS, SENILE OSTEOPOROSIS, AND GLUCOCORTICOID-INDUCED OSTEOPOROSIS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-17 | — | — | US | disclosed |