Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 4/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | TTR | P02766 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267705 | 0.89 | EYA3 (0.55) | EYA3SLC22A12CYP2C19TTRCYP2C9 | |
| SCHEMBL9605230 | 0.88 | EYA3 (0.43) | EYA3SLC22A12CYP2C19TTRCYP2C9 | |
| SCHEMBL2141567 | 0.83 | EYA3 (0.69) | EYA3SLC22A12CYP2C19TTRCYP2C9 | |
| SCHEMBL4670184 | 0.80 | EYA3 (0.66) | EYA3SLC22A12CYP2C19TTRCYP2C9 | |
| Hydrochloric Acid SCHEMBL9350957 | 0.79 | EYA3 (0.64) | EYA3SLC22A12CYP2C19TTRCYP2C9 | |
| SCHEMBL10599107 | 0.79 | CYP2C19 (0.63) | EYA3SLC22A12CYP2C19CYP2C9MEN1 | |
| SCHEMBL10602010 | 0.78 | CYP2C19 (0.46) | EYA3SLC22A12CYP2C19TTRCYP2C9 | |
| SCHEMBL10598815 | 0.77 | EYA3 (0.54) | EYA3SLC22A12CYP2C19CYP2C9PTPN1 | |
| Hydrochloric Acid SCHEMBL9347221 | 0.76 | CYP2C9 (0.58) | EYA3SLC22A12CYP2C19TTRCYP2C9 | |
| SCHEMBL9287304 | 0.76 | EYA3 (0.53) | EYA3SLC22A12CYP2C19TTRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699772-B1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | CLARIANT SPECIALTY FINE CHEM F (FR) | 2013-02-20 | — | — | EP | claimed |
| EP-2508517-A1 | Process for the preparation of N-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | Clariant Specialty Fine Chemicals (France) (FR) | 2012-10-10 | — | — | EP | claimed |
| US-7544817-B2 | Process for the preparation of n-alkyl-2(hydroxy-4benzoyl)-3 benzofurans and intermediates thereof | CLARIANT (FRANCE) (FR) | 2009-06-09 | — | — | US | claimed |
| US-20070155831-A1 | Process for the preparation of n-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | WEYLCHEM LAMOTTE S.A.S. (FR) | 2007-07-05 | — | — | US | claimed |
| EP-1699772-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | Clariant (France) S.A. (FR) | 2006-09-13 | — | — | EP | claimed |
| WO-2005066149-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | CLARIANT (FRANCE) (FR) | 2005-07-21 | — | — | WO | claimed |
| EP-1699772-B1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | CLARIANT SPECIALTY FINE CHEM F (FR) | 2013-02-20 | — | — | EP | disclosed |
| EP-2508517-A1 | Process for the preparation of N-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | Clariant Specialty Fine Chemicals (France) (FR) | 2012-10-10 | — | — | EP | disclosed |
| US-7544817-B2 | Process for the preparation of n-alkyl-2(hydroxy-4benzoyl)-3 benzofurans and intermediates thereof | CLARIANT (FRANCE) (FR) | 2009-06-09 | — | — | US | disclosed |
| US-20070155831-A1 | Process for the preparation of n-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | WEYLCHEM LAMOTTE S.A.S. (FR) | 2007-07-05 | — | — | US | disclosed |
| EP-1699772-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | Clariant (France) S.A. (FR) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005066149-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | CLARIANT (FRANCE) (FR) | 2005-07-21 | — | — | WO | disclosed |
| EP-0380588-B1 | CERTAIN 3-SUBSTITUTED 2-ALKYL BENZOFURAN DERIVATIVES | RES CORP TECHNOLOGIES INC (US) | 1994-11-09 | — | — | EP | disclosed |
| US-5266711-A | Process for the preparation of 3-benzoyl benzofuran derivatives | SANOFI (FR) | 1993-11-30 | — | — | US | disclosed |
| EP-0380588-A4 | CERTAIN 3-SUBSTITUTED 2-ALKYL BENZOFURAN DERIVATIVES | — | 1991-04-03 | — | — | EP | disclosed |
| EP-0380588-A1 | CERTAIN 3-SUBSTITUTED 2-ALKYL BENZOFURAN DERIVATIVES. | UNIV TENNESSEE RES CORP (US) | 1990-08-08 | — | — | EP | disclosed |
| US-4851554-A | Certain 3-substituted 2-alkyl benzofuran derivatives | UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| WO-1989002892-A1 | CERTAIN 3-SUBSTITUTED 2-ALKYL BENZOFURAN DERIVATIVES | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 1989-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155831-A1 | Process for the preparation of n-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | CYP2F1, CYP2E1, CYP1B1 | EYA3 4838/4885SLC22A12 3418/4885CYP2C19 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.