Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 8/20 | 0.69 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.57 |
| ▸ | TTR | P02766 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267705 | 0.90 | EYA3 (0.55) | EYA3SLC22A12PTPN1CYP2C19CYP2C9 | |
| SCHEMBL10599107 | 0.85 | CYP2C19 (0.63) | EYA3SLC22A12PTPN1CYP2C19CYP2C9 | |
| SCHEMBL10598815 | 0.83 | EYA3 (0.54) | EYA3SLC22A12PTPN1CYP2C19CYP2C9 | |
| SCHEMBL4430343 | 0.83 | EYA3 (0.44) | EYA3SLC22A12PTPN1CYP2C19CYP2C9 | |
| Benzarone SCHEMBL555497 | 0.82 | EYA3 (1.00) | EYA3SLC22A12PTPN1CYP2C19CYP2C9 | |
| Benzarone SCHEMBL29576057 | 0.82 | EYA3 (1.00) | EYA3SLC22A12PTPN1CYP2C19CYP2C9 | |
| Benzarone SCHEMBL28587332 | 0.81 | EYA3 (0.97) | EYA3SLC22A12PTPN1CYP2C19CYP2C9 | |
| SCHEMBL3130469 | 0.81 | EYA3 (0.72) | EYA3SLC22A12PTPN1CYP2C19CYP2C9 | |
| SCHEMBL9605230 | 0.80 | EYA3 (0.43) | EYA3SLC22A12PTPN1CYP2C19CYP2C9 | |
| SCHEMBL11840583 | 0.80 | EYA3 (0.85) | EYA3SLC22A12PTPN1CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699772-B1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | CLARIANT SPECIALTY FINE CHEM F (FR) | 2013-02-20 | — | — | EP | claimed |
| US-20070155831-A1 | Process for the preparation of n-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | WEYLCHEM LAMOTTE S.A.S. (FR) | 2007-07-05 | — | — | US | claimed |
| EP-1699772-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | Clariant (France) S.A. (FR) | 2006-09-13 | — | — | EP | claimed |
| WO-2005066149-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | CLARIANT (FRANCE) (FR) | 2005-07-21 | — | — | WO | claimed |
| EP-0210156-B1 | MOLECULAR COMPLEXES FORMED FROM A BENZOFURANE DERIVATIVE AND ALUMINIUM CHLORIDE, THEIR PREPARATION AND THEIR USE | SANOFI (FR) | 1989-01-25 | — | — | EP | claimed |
| US-4766223-A | FROM ALKYL BENZOFURAN AND 4-METHOXYBENZOYL HALIDE; HYDROLYSIS, DEMETHYLATION | SANOFI (FR) | 1988-08-23 | — | — | US | claimed |
| EP-1699772-B1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | CLARIANT SPECIALTY FINE CHEM F (FR) | 2013-02-20 | — | — | EP | disclosed |
| EP-2508517-A1 | Process for the preparation of N-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | Clariant Specialty Fine Chemicals (France) (FR) | 2012-10-10 | — | — | EP | disclosed |
| EP-2508517-A1 | Process for the preparation of N-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | Clariant Specialty Fine Chemicals (France) (FR) | 2012-10-10 | — | — | EP | disclosed |
| JP-2012012400-A | METHOD FOR PREPARING N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURAN AND INTERMEDIATE THEREOF | CLARIANT SPECIALTY FINE CHEMICALS (FRANCE) | 2012-01-19 | — | — | JP | disclosed |
| US-7544817-B2 | Process for the preparation of n-alkyl-2(hydroxy-4benzoyl)-3 benzofurans and intermediates thereof | CLARIANT (FRANCE) (FR) | 2009-06-09 | — | — | US | disclosed |
| US-7544817-B2 | Process for the preparation of n-alkyl-2(hydroxy-4benzoyl)-3 benzofurans and intermediates thereof | CLARIANT (FRANCE) (FR) | 2009-06-09 | — | — | US | disclosed |
| CN-100475801-C | Process for preparing 2-n-alkyl-3- (4-hydroxybenzoyl) benzofuran and intermediates thereof | CLARIANT FRANCE SA (FR) | 2009-04-08 | — | — | CN | disclosed |
| EP-1699772-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | Clariant (France) S.A. (FR) | 2006-09-13 | — | — | EP | disclosed |
| EP-1699772-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | Clariant (France) S.A. (FR) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005066149-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | CLARIANT (FRANCE) (FR) | 2005-07-21 | — | — | WO | disclosed |
| WO-2005066149-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | CLARIANT (FRANCE) (FR) | 2005-07-21 | — | — | WO | disclosed |
| US-4766223-A | FROM ALKYL BENZOFURAN AND 4-METHOXYBENZOYL HALIDE; HYDROLYSIS, DEMETHYLATION | SANOFI (FR) | 1988-08-23 | — | — | US | disclosed |
| US-4766223-A | FROM ALKYL BENZOFURAN AND 4-METHOXYBENZOYL HALIDE; HYDROLYSIS, DEMETHYLATION | SANOFI (FR) | 1988-08-23 | — | — | US | disclosed |
| US-4766223-A | FROM ALKYL BENZOFURAN AND 4-METHOXYBENZOYL HALIDE; HYDROLYSIS, DEMETHYLATION | SANOFI (FR) | 1988-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155831-A1 | Process for the preparation of n-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | CYP2F1, CYP2E1, CYP1B1 | EYA3 4838/4885SLC22A12 3418/4885PTPN1 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.