Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480610 | 0.89 | LMNA (0.45) | LMNAHDAC1HDAC6KMT2ACA1 | |
| SCHEMBL1852520 | 0.87 | LMNA (0.46) | LMNAHDAC1HDAC6KMT2ACA1 | |
| SCHEMBL4418249 | 0.86 | KMT2A (0.56) | LMNAHDAC1HDAC6KMT2ANR1H4 | |
| SCHEMBL13930174 | 0.81 | LMNA (0.41) | LMNAHDAC1HDAC6KMT2ACA1 | |
| SCHEMBL15197912 | 0.80 | CYP2D6 (0.46) | LMNAHDAC1HDAC6CA1CA2 | |
| SCHEMBL19971919 | 0.76 | LMNA (0.39) | LMNAHDAC1HDAC6KMT2ACA1 | |
| SCHEMBL31393489 | 0.75 | LMNA (0.44) | LMNAHDAC1HDAC6KMT2ACA1 | |
| SCHEMBL10946280 | 0.75 | LMNA (0.59) | LMNAKMT2APLA2G2APLA2G10HNF4A | |
| SCHEMBL1296450 | 0.74 | CA1 (0.63) | LMNACA1CA2CA9PRSS1 | |
| SCHEMBL23928101 | 0.74 | LMNA (0.37) | LMNAHDAC1HDAC6KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442005-B1 | NOVEL DIFUNCTIONAL PHOTOINITIATORS | CIBA HOLDING INC (CH) | 2009-03-18 | — | — | EP | disclosed |
| US-20060209098-A1 | Radiation curable ink-jet ink containing an alpha hydroxy ketone as photoinitiator | FUCHS ANDRE | 2006-09-21 | — | — | US | disclosed |
| US-7084183-B2 | Difunctional photoinitiators | CIBA SPECIALTY CHEMCIALS CORP. (US) | 2006-08-01 | — | — | US | disclosed |
| CN-1771308-A | Radiation curable inkjet inks containing alpha-hydroxy ketones as photoinitiators | CIBA SC HOLDING AG (CH) | 2006-05-10 | — | — | CN | disclosed |
| CN-1249009-C | Novel bifunctional photoinitiators | CIBA SC HOLDING AG (CH) | 2006-04-05 | — | — | CN | disclosed |
| EP-1613706-A1 | RADIATION CURABLE INK-JET INK CONTAINING AN ALPHA HYDROXY KETONE AS PHOTOINITIATOR | Ciba SC Holding AG (CH) | 2006-01-11 | — | — | EP | disclosed |
| CN-1582267-A | Novel bifunctional photoinitiators | CIBA SC HOLDING AG (CH) | 2005-02-16 | — | — | CN | disclosed |
| US-20050004249-A1 | Novel disfunctional photoinitiators | IGM GROUP B.V. (NL) | 2005-01-06 | — | — | US | disclosed |
| WO-2004092287-A1 | RADIATION CURABLE INK-JET INK CONTAINING AN ALPHA HYDROXY KETONE AS PHOTOINITIATOR | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-10-28 | — | — | WO | disclosed |
| EP-1442005-A2 | NOVEL DIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003040076-A2 | NOVEL DIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004249-A1 | Novel disfunctional photoinitiators | ETFA, ETFB, PAH | LMNA 2221/4885HDAC1 959/4885HDAC6 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.