Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430370 | 0.86 | LMNA (0.46) | KMT2ALMNAELANEPLA2G10PLA2G2A | |
| SCHEMBL6687329 | 0.85 | ALDH1A1 (0.57) | LMNAPLK1ALDH1A1RXRARXRB | |
| SCHEMBL3671949 | 0.85 | CES2 (0.52) | KMT2ALMNAHDAC6PLK1THRA | |
| SCHEMBL480674 | 0.85 | KMT2A (0.54) | KMT2ALMNAELANESRD5A2PLA2G10 | |
| SCHEMBL7495525 | 0.83 | IDO1 (0.41) | KMT2AHDAC6PLK1THRATHRB | |
| SCHEMBL153898 | 0.83 | KMT2A (0.56) | KMT2ALMNAELANESRD5A2PLA2G10 | |
| SCHEMBL3976359 | 0.82 | NR1H4 (0.51) | LMNASRD5A2ALDH1A1EPHX2NR1H4 | |
| SCHEMBL3974638 | 0.82 | KMT2A (0.49) | KMT2APLK1THRATHRB | |
| SCHEMBL13175610 | 0.80 | ALDH1A1 (0.52) | PLK1ALDH1A1RXRARXRB | |
| SCHEMBL3673193 | 0.80 | PTGS1 (0.49) | KMT2ALMNAALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620475-B1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2009-11-11 | — | — | EP | disclosed |
| US-7462650-B2 | Trifunctional photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-12-09 | — | — | US | disclosed |
| US-20060270748-A1 | Novel trifunctional photoinitiators | IGM GROUP B.V. (NL) | 2006-11-30 | — | — | US | disclosed |
| EP-1620475-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099262-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-11-18 | — | — | WO | disclosed |