Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430370 | 0.89 | LMNA (0.46) | LMNAHDAC1HDAC6CA1CA2 | |
| SCHEMBL10946280 | 0.87 | LMNA (0.59) | LMNAKMT2APLA2G2APLA2G10HNF4A | |
| SCHEMBL480674 | 0.87 | KMT2A (0.54) | LMNAHDAC1HDAC6CA1CA2 | |
| SCHEMBL1852520 | 0.86 | LMNA (0.46) | LMNAHDAC1HDAC6CA1CA2 | |
| SCHEMBL13930174 | 0.80 | LMNA (0.41) | LMNAHDAC1HDAC6CA1CA2 | |
| SCHEMBL15197912 | 0.78 | CYP2D6 (0.46) | LMNAHDAC1HDAC6CA1CA2 | |
| SCHEMBL3682129 | 0.76 | PLK1 (0.40) | HDAC1KMT2ANR1H4 | |
| SCHEMBL7136015 | 0.75 | PRSS1 (0.47) | LMNAHDAC1HDAC6CA1CA2 | |
| SCHEMBL19971919 | 0.75 | LMNA (0.39) | LMNAHDAC1HDAC6CA1CA2 | |
| SCHEMBL27627345 | 0.74 | ALDH1A1 (0.55) | LMNARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411359-B1 | NOVEL OLIGOFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2017-02-01 | — | — | EP | disclosed |
| US-8604251-B2 | Oligofunctional photoinitiators | BASF SE (DE) | 2013-12-10 | — | — | US | disclosed |
| US-20120029107-A1 | NOVEL OLIGOFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2012-02-02 | — | — | US | disclosed |
| EP-2411359-A1 | NOVEL OLIGOFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108862-A1 | NOVEL OLIGOFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2010-09-30 | — | — | WO | disclosed |
| EP-1620475-B1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2009-11-11 | — | — | EP | disclosed |
| EP-1442005-B1 | NOVEL DIFUNCTIONAL PHOTOINITIATORS | CIBA HOLDING INC (CH) | 2009-03-18 | — | — | EP | disclosed |
| US-7462650-B2 | Trifunctional photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-12-09 | — | — | US | disclosed |
| US-20060270748-A1 | Novel trifunctional photoinitiators | IGM GROUP B.V. (NL) | 2006-11-30 | — | — | US | disclosed |
| US-20060209098-A1 | Radiation curable ink-jet ink containing an alpha hydroxy ketone as photoinitiator | FUCHS ANDRE | 2006-09-21 | — | — | US | disclosed |
| CN-1771308-A | Radiation curable inkjet inks containing alpha-hydroxy ketones as photoinitiators | CIBA SC HOLDING AG (CH) | 2006-05-10 | — | — | CN | disclosed |
| CN-1249009-C | Novel bifunctional photoinitiators | CIBA SC HOLDING AG (CH) | 2006-04-05 | — | — | CN | disclosed |
| EP-1620475-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2006-02-01 | — | — | EP | disclosed |
| EP-1613706-A1 | RADIATION CURABLE INK-JET INK CONTAINING AN ALPHA HYDROXY KETONE AS PHOTOINITIATOR | Ciba SC Holding AG (CH) | 2006-01-11 | — | — | EP | disclosed |
| CN-1582267-A | Novel bifunctional photoinitiators | CIBA SC HOLDING AG (CH) | 2005-02-16 | — | — | CN | disclosed |
| US-20050004249-A1 | Novel disfunctional photoinitiators | IGM GROUP B.V. (NL) | 2005-01-06 | — | — | US | disclosed |
| WO-2004099262-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-11-18 | — | — | WO | disclosed |
| WO-2004092287-A1 | RADIATION CURABLE INK-JET INK CONTAINING AN ALPHA HYDROXY KETONE AS PHOTOINITIATOR | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-10-28 | — | — | WO | disclosed |
| EP-1442005-A2 | NOVEL DIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003040076-A2 | NOVEL DIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029107-A1 | NOVEL OLIGOFUNCTIONAL PHOTOINITIATORS | CCNA1, CCNT1, TET1 | LMNA 4153/4885HDAC1 1948/4885HDAC6 4074/4885 |
| US-20050004249-A1 | Novel disfunctional photoinitiators | ETFA, ETFB, PAH | LMNA 2221/4885HDAC1 959/4885HDAC6 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.