SCHEMBL4430378

SCHEMBL4430378

CC(C)CCCC(C)CCOc1cc(Br)ccc1/C=C/c1ccc(Br)cc1OCCC(C)CCCC(C)C

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.37
HPGD P15428 2/20 0.36
LMNA P02545 1/20 0.35
FDPS P14324 2/20 0.35
ALOX5 P09917 1/20 0.35
TSHR P16473 1/20 0.34
AR P10275 2/20 0.34
EGFR P00533 1/20 0.34
APP P05067 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
HDAC8 Q9BY41 2/20 0.33
GGPS1 O95749 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GSTO1 P78417 1/20 0.32
HTT P42858 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4430381 1.00 TLR8 (0.37) TLR8HPGDLMNAFDPSALOX5
SCHEMBL4434696 0.97 TLR8 (0.36) TLR8HPGDLMNAFDPSALOX5
SCHEMBL2906169 0.86 LMNA (0.37) TLR8HPGDLMNAFDPSALOX5
SCHEMBL4563654 0.86 LMNA (0.37) TLR8HPGDLMNAFDPSALOX5
SCHEMBL1956965 0.82 ALOX5 (0.41) TLR8HPGDLMNAFDPSALOX5
SCHEMBL2903065 0.81 CHRNA7 (0.36) TLR8LMNAFDPSALOX5EGFR
SCHEMBL2903068 0.81 CHRNA7 (0.36) TLR8LMNAFDPSALOX5EGFR
SCHEMBL7585689 0.79 GSTO1 (0.45) LMNAFDPSALOX5GGPS1NPSR1
SCHEMBL4434693 0.78 ALOX5 (0.36) TLR8HPGDLMNAFDPSALOX5
SCHEMBL11957249 0.77 HTR2A (0.37) HPGDLMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1074600-B1 Polymeric fluorescent substance and polymer light emitting device SUMITOMO CHEMICAL CO (JP) 2009-06-03 EP disclosed
US-6984459-B1 Polymeric fluorescent substance and polymer light emitting device SUMITO CHEMICAL COMPANY, LIMITED (JP) 2006-01-10 US disclosed
EP-1074600-A2 Polymeric fluorescent substance and polymer light emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-07 EP disclosed