SCHEMBL4434693

SCHEMBL4434693

C=C(c1ccc(Br)cc1OCCC(C)CCCC(C)C)c1cc(OCCC(C)CCCC(C)C)c(C(=C)c2ccc(Br)cc2OCCC(C)CCCC(C)C)cc1OCCC(C)CCCC(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.36
FDPS P14324 2/20 0.34
HTT P42858 3/20 0.33
FOLH1 Q04609 1/20 0.32
GGPS1 O95749 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GSTO1 P78417 1/20 0.32
EGFR P00533 2/20 0.32
C5 P01031 1/20 0.32
TLR8 Q9NR97 1/20 0.32
LMNA P02545 2/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
XDH P47989 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2906169 0.80 LMNA (0.37) ALOX5FDPSHTTGGPS1NPSR1
SCHEMBL4563654 0.80 LMNA (0.37) ALOX5FDPSHTTGGPS1NPSR1
SCHEMBL4430381 0.78 TLR8 (0.37) ALOX5FDPSHTTGGPS1NPSR1
SCHEMBL4430378 0.78 TLR8 (0.37) ALOX5FDPSHTTGGPS1NPSR1
SCHEMBL4434696 0.76 TLR8 (0.36) ALOX5FDPSHTTGGPS1NPSR1
SCHEMBL6852447 0.74 TDP1 (0.50) ALOX5FDPSGGPS1LMNATDP1
SCHEMBL7585689 0.74 GSTO1 (0.45) ALOX5FDPSHTTGGPS1NPSR1
SCHEMBL14245331 0.72 LMNA (0.43) ALOX5FDPSHTTGGPS1GSTO1
SCHEMBL1956731 0.72 LMNA (0.43) ALOX5FDPSHTTGGPS1TLR8
SCHEMBL2306206 0.71 HTT (0.50) ALOX5FDPSHTTGGPS1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1074600-B1 Polymeric fluorescent substance and polymer light emitting device SUMITOMO CHEMICAL CO (JP) 2009-06-03 EP disclosed
US-6984459-B1 Polymeric fluorescent substance and polymer light emitting device SUMITO CHEMICAL COMPANY, LIMITED (JP) 2006-01-10 US disclosed
EP-1074600-A2 Polymeric fluorescent substance and polymer light emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-07 EP disclosed