SCHEMBL4430762

SCHEMBL4430762

O=C(O)c1cccc(-c2ccccc2CCc2ccccc2)c1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.55
ALDH1A1 P00352 3/20 0.49
ADRB2 P07550 1/20 0.49
HTT P42858 1/20 0.48
BID P55957 1/20 0.48
BCL2L1 Q07817 1/20 0.48
MCL1 Q07820 1/20 0.48
BAK1 Q16611 1/20 0.48
PPARA Q07869 1/20 0.46
MAPT P10636 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 2/20 0.43
TSHR P16473 1/20 0.43
KDM4E B2RXH2 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SOX18 P35713 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3001321 0.88 FOLH1 (0.55) FOLH1ALDH1A1ADRB2HTTBID
SCHEMBL8768031 0.81 FOLH1 (0.55) FOLH1ALDH1A1MCL1MAPTLMNA
SCHEMBL38662910 0.81 BID (0.52) FOLH1BIDBCL2L1MCL1BAK1
SCHEMBL3706715 0.81 BID (0.52) FOLH1BIDBCL2L1MCL1BAK1
Diphenylmethane SCHEMBL22720596 0.81 FOLH1 (0.54) FOLH1ALDH1A1MAPTLMNATSHR
SCHEMBL29975597 0.81 FOLH1 (0.66) FOLH1ALDH1A1ADRB2HTTMAPT
SCHEMBL166927 0.81 FOLH1 (0.66) FOLH1ALDH1A1ADRB2HTTMAPT
SCHEMBL1854604 0.81 KMT2A (0.49) FOLH1ALDH1A1ADRB2HTTBID
SCHEMBL28522033 0.80 FOLH1 (0.54) FOLH1ALDH1A1MAPTLMNATSHR
SCHEMBL8702953 0.79 FOLH1 (0.63) FOLH1ALDH1A1ADRB2HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1644437-A4 LOW GLOW OLEFIN FERRO CORP (US) 2009-02-18 EP disclosed
EP-1599544-A4 GLASS REINFORCED NYLON BLEND WITH IMPROVED KNITLINE STRENGTH FERRO CORP (US) 2007-05-02 EP disclosed
US-7176607-B2 Light fixture with reflective polymeric composition and pigment package FERRO CORPORATION (US) 2007-02-13 US disclosed
EP-1579147-A4 LIGHT REFLECTING POLYMERIC COMPOSITIONS FERRO CORP (US) 2006-05-17 EP disclosed
EP-1644437-A1 LOW GLOW OLEFIN FERRO CORPORATION (US) 2006-04-12 EP disclosed
US-7026391-B2 Polymer compositions comprising polyolefins and reaction products of a polyolefin and an unsaturated carboxylic reagent and articles made therefrom FERRO CORPORATION (US) 2006-04-11 US disclosed
EP-1599544-A1 GLASS REINFORCED NYLON BLEND WITH IMPROVED KNITLINE STRENGTH FERRO CORPORATION (US) 2005-11-30 EP disclosed
EP-1579147-A1 LIGHT REFLECTING POLYMERIC COMPOSITIONS FERRO CORPORATION (US) 2005-09-28 EP disclosed
US-20050095534-A1 Light reflecting polymeric compositions FERRO CORPORATION (US) 2005-05-05 US disclosed
WO-2005007736-A1 LOW GLOW OLEFIN FERRO CORPORATION (US) 2005-01-27 WO disclosed
US-20050014888-A1 Low gloss olefin FERRO CORPORATION (US) 2005-01-20 US disclosed
US-6838494-B2 Light reflecting polymeric compositions FERRO CORPORATION (US) 2005-01-04 US disclosed
WO-2004078848-A1 GLASS REINFORCED NYLON BLEND WITH IMPROVED KNITLINE STRENGTH FERRO CORPORATION (US) 2004-09-16 WO disclosed
WO-2004061366-A1 LIGHT REFLECTING POLYMERIC COMPOSITIONS FERRO CORPORATION (US) 2004-07-22 WO disclosed
US-6759474-B1 POLYAMIDE, POLYPROPYLENE AND BLOCK COPOLYMER INCLUDING VINYL AROMATIC, CONJUGATED DIENE AND UNSATURATED DICARBOXYLIC MONOMERS; DROP IMPACT STRENGTH FERRO CORPORATION 2004-07-06 US disclosed
US-20040125603-A1 Light reflecting polymeric compositions FERRO CORPORATION 2004-07-01 US disclosed
US-20030004245-A1 Polymer compositions comprising polyolefins and reaction products of a polyolefin and an unsaturated carboxylic reagent and articles made therefrom LYONDELLBASELL ADVANCED POLYMERS INC. 2003-01-02 US disclosed
US-5317059-A Impact-resistant polymer blends of olefin polymers, polyamides, and terpolymer compatibilizers FERRO CORPORATION (US) 1994-05-31 US disclosed
US-5278231-A Comprising hydrogenated block copolymer FERRO CORPORATION (US) 1994-01-11 US disclosed
WO-1992022607-A1 HIGH SURFACE ENERGY POLYOLEFIN BLEND COMPOSITIONS THE FERRO CORPORATION (US) 1992-12-23 WO disclosed