Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746965 | 1.00 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL12648656 | 0.79 | TSHR (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL2553076 | 0.79 | TSHR (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL336361 | 0.79 | TSHR (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL336363 | 0.79 | TSHR (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL1130719 | 0.79 | TSHR (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL5019049 | 0.79 | TSHR (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL2367279 | 0.79 | TSHR (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL336362 | 0.79 | TSHR (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL13517377 | 0.79 | TSHR (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947858-A | Compounds selectively inhibiting four amino acid modifications of ADP, preparation and application thereof | 首都医科大学 | 2023-10-27 | — | — | CN | disclosed |
| EP-2101571-A1 | NON-STANDARD AMINO ACID CONJUGATES OF AMPHETAMINE AND PROCESSES FOR MAKING AND USING THE SAME | Kempharm, Inc. (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008073918-A1 | NON-STANDARD AMINO ACID CONJUGATES OF AMPHETAMINE AND PROCESSES FOR MAKING AND USING THE SAME | KEMPHARM, INC. (US) | 2008-06-19 | — | — | WO | disclosed |