D,L-Threo-3-Hydroxyaspartic Acid

D,L-Threo-3-Hydroxyaspartic Acid

SCHEMBL336362

N[C@H](C(=O)O)[C@@H](O)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
SLC7A5 Q01650 1/20 0.50
USP2 O75604 1/20 0.44
SLCO1B1 Q9Y6L6 1/20 0.44
SLC1A3 P43003 5/20 0.42
SLC1A2 P43004 5/20 0.42
SLC1A1 P43005 5/20 0.42
TP53 P04637 1/20 0.37
CYP2C9 P11712 2/20 0.36
PDE4A P27815 1/20 0.36
PTGS1 P23219 2/20 0.35
NR1I2 O75469 1/20 0.35
ADRA1A P35348 1/20 0.35
LMNA P02545 1/20 0.35
BLM P54132 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SLC7A11 Q9UPY5 1/20 0.35
MEN1 O00255 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL2367279 1.00 TSHR (0.56) TSHRSLC7A5USP2SLCO1B1SLC1A3
D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL336363 1.00 TSHR (0.56) TSHRSLC7A5USP2SLCO1B1SLC1A3
D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL13517377 1.00 TSHR (0.56) TSHRSLC7A5USP2SLCO1B1SLC1A3
D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL5019049 1.00 TSHR (0.56) TSHRSLC7A5USP2SLCO1B1SLC1A3
D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL2553076 1.00 TSHR (0.56) TSHRSLC7A5USP2SLCO1B1SLC1A3
D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL336361 1.00 TSHR (0.56) TSHRSLC7A5USP2SLCO1B1SLC1A3
D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL1130719 1.00 TSHR (0.56) TSHRSLC7A5USP2SLCO1B1SLC1A3
D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL12648656 1.00 TSHR (0.56) TSHRSLC7A5USP2SLCO1B1SLC1A3
D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL16237980 0.97 TSHR (0.53) TSHRSLC7A5USP2SLCO1B1SLC1A3
D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL8200338 0.97 TSHR (0.53) TSHRSLC7A5USP2SLCO1B1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 931 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552839-B2 Cyclic peptides for protection against respiratory syncytial virus VIROMETIX AG (CH) 2026-02-17 US claimed
US-20240287143-A1 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS Universität Zürich (CH) 2024-08-29 US claimed
EP-4295866-A2 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS Virometix AG (CH) 2023-12-27 EP claimed
EP-3638284-B1 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS VIROMETIX AG (CH) 2023-08-30 EP claimed
US-11680085-B2 Cyclic peptides for protection against respiratory syncytial virus VIROMETIX AG (CH) 2023-06-20 US claimed
CN-114728044-A Modified factor VII polypeptides for subcutaneous administration and on-demand treatment 介控生化科技公司 2022-07-08 CN claimed
US-20210187083-A1 MODIFIED FACTOR VII POLYPEPTIDES FOR SUBCUTANEOUS ADMINISTRATION AND ON-DEMAND TREATMENT OAKTREE FUND ADMINISTRATION, LLC 2021-06-24 US claimed
EP-3833381-A1 MODIFIED FACTOR VII POLYPEPTIDES FOR SUBCUTANEOUS ADMINISTRATION AND ON-DEMAND TREATMENT Catalyst Biosciences, Inc. (US) 2021-06-16 EP claimed
US-20210101941-A1 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS Universität Zürich (CH) 2021-04-08 US claimed
US-20210069306-A1 MODIFIED FACTOR VII POLYPEPTIDES FOR SUBCUTANEOUS ADMINISTRATION AND ON-DEMAND TREATMENT GC BIOPHARMA CORP. (KR) 2021-03-11 US claimed
US-5648455-A TREATMENT OF DRUG RESISTANT BACTERIA WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) 1997-07-15 US claimed
CN-1132252-A Antibiotic WAP-8294A, process for its preparation and antibacterial composition WAKAMOTO PHARMA CO LTD (JP) 1996-10-02 CN claimed
US-5518906-A MUTANT ESCHERICHIA MICROBE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-05-21 US claimed
EP-0668358-A1 Antibiotic WAP-8294A, method for preparing the same and antibacterial composition Wakamoto Pharmaceutical Co., Ltd. (JP) 1995-08-23 EP claimed
CN-1095105-A Production of D-pantoic acid and D-pantothenic acid TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1994-11-16 CN claimed
EP-0590857-A2 Production of D-pantoic acid and D-pantothenic acid TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-06 EP claimed
WO-1992019717-A1 A HIGH-AFFINITY HUMAN GLUTAMATE/ASPARTATE UPTAKE SYSTEM BAYLOR COLLEGE OF MEDICINE (US) 1992-11-12 WO claimed
US-4452782-A IMMUNOPOTENTIATING AGENTS HOFFMANN-LA ROCHE INC. (US) 1984-06-05 US claimed
EP-0019072-B1 PENTADECAPEPTIDE, PROCESS FOR THE PREPARATION THEREOF AND IMMUNOPOTENTIATING AGENT F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-09-14 EP claimed
EP-0019072-A1 Pentadecapeptide, process for the preparation thereof and immunopotentiating agent F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-11-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11680085-B2 Cyclic peptides for protection against respiratory syncytial virus VIP, LNPEP, CSTB TSHR 2352/4885SLC7A5 2179/4885USP2 1775/4885
US-20240287143-A1 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS VIP, QPCT, QPCTL TSHR 1073/4885SLC7A5 196/4885USP2 1530/4885
US-20210101941-A1 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS QPCT, QPCTL, VIP TSHR 2209/4885SLC7A5 277/4885USP2 1808/4885
US-12552839-B2 Cyclic peptides for protection against respiratory syncytial virus CTH, VIP, CXCL10 TSHR 1606/4885SLC7A5 37/4885USP2 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.