Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL2367279 | 1.00 | TSHR (0.56) | TSHRSLC7A5USP2SLCO1B1SLC1A3 | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL336363 | 1.00 | TSHR (0.56) | TSHRSLC7A5USP2SLCO1B1SLC1A3 | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL336362 | 1.00 | TSHR (0.56) | TSHRSLC7A5USP2SLCO1B1SLC1A3 | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL13517377 | 1.00 | TSHR (0.56) | TSHRSLC7A5USP2SLCO1B1SLC1A3 | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL2553076 | 1.00 | TSHR (0.56) | TSHRSLC7A5USP2SLCO1B1SLC1A3 | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL336361 | 1.00 | TSHR (0.56) | TSHRSLC7A5USP2SLCO1B1SLC1A3 | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL1130719 | 1.00 | TSHR (0.56) | TSHRSLC7A5USP2SLCO1B1SLC1A3 | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL12648656 | 1.00 | TSHR (0.56) | TSHRSLC7A5USP2SLCO1B1SLC1A3 | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL16237980 | 0.97 | TSHR (0.53) | TSHRSLC7A5USP2SLCO1B1SLC1A3 | |
| D,L-Threo-3-Hydroxyaspartic Acid SCHEMBL8200338 | 0.97 | TSHR (0.53) | TSHRSLC7A5USP2SLCO1B1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11939583-B2 | Method of producing autotrophic organisms with altered photorespiration and improved CO2 fixation | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2024-03-26 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20220145339-A1 | METHOD FOR PREPARATION OF PRIMARY AMINE COMPOUNDS | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2022-05-12 | — | — | US | disclosed |
| US-20210163956-A1 | METHOD OF PRODUCING AUTOTROPHIC ORGANISMS WITH ALTERED PHOTORESPIRATION AND IMPROVED CO2 FIXATION | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-06-03 | — | — | US | disclosed |
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| WO-2010054102-A2 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCB1, SLC47A1 | TSHR 4679/4885SLC7A5 414/4885USP2 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.