Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | SGMS2 | Q8NHU3 | 6/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947857 | 0.87 | SGMS2 (0.60) | NPC1SGMS2GAAHTTKMT2A | |
| SCHEMBL7531833 | 0.86 | SGMS2 (0.58) | NPC1SGMS2GAAHTTKMT2A | |
| SCHEMBL3679181 | 0.85 | SGMS2 (0.60) | NPC1SGMS2GAAHTTKMT2A | |
| SCHEMBL19156329 | 0.83 | SGMS2 (0.59) | NPC1SGMS2GAAHTTKMT2A | |
| SCHEMBL4944383 | 0.83 | NPC1 (0.60) | NPC1SGMS2GAAHTTKMT2A | |
| SCHEMBL30194507 | 0.83 | SGMS2 (0.59) | NPC1SGMS2GAAHTTKMT2A | |
| SCHEMBL4431127 | 0.83 | SGMS2 (0.59) | NPC1SGMS2GAAHTTKMT2A | |
| SCHEMBL14339650 | 0.83 | SGMS2 (0.59) | NPC1SGMS2GAAHTTKMT2A | |
| SCHEMBL2999130 | 0.83 | SGMS2 (0.59) | NPC1SGMS2GAAHTTKMT2A | |
| SCHEMBL7344495 | 0.83 | SGMS2 (0.59) | NPC1SGMS2GAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556085-A2 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Wellstat Therapeutics Corporation (US) | 2005-07-27 | — | — | EP | claimed |
| WO-2004041165-A2 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2004-05-21 | — | — | WO | claimed |