Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182720 | 0.87 | HSP90AA1 (0.66) | HSP90AA1CA1CA2FAAHPRSS1 | |
| SCHEMBL17865800 | 0.77 | KDM4E (0.49) | HSP90AA1NAMPTHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL27966141 | 0.75 | HSP90AA1 (0.44) | HSP90AA1NAMPTHPGDSMN1; SMN2POLB | |
| SCHEMBL11182611 | 0.72 | CYP1A2 (0.49) | HSP90AA1NAMPTUSP2HPGDHSD17B10 | |
| SCHEMBL29482080 | 0.72 | TSHR (0.58) | NAMPTCA1CA2FAAHPRSS1 | |
| SCHEMBL10597184 | 0.69 | HSP90AA1 (0.58) | HSP90AA1CA1CA2FAAHPRSS1 | |
| SCHEMBL29525469 | 0.69 | NAMPT (0.43) | NAMPTPKMUSP2HPGDHSD17B10 | |
| SCHEMBL7095387 | 0.69 | ALDH1A1 (0.60) | NAMPTPKMHPGDSMN1; SMN2LMNA | |
| SCHEMBL3174757 | 0.69 | HSP90AA1 (0.57) | HSP90AA1CA1CA2FAAHPRSS1 | |
| SCHEMBL6503919 | 0.69 | HSP90AA1 (0.57) | HSP90AA1CA1CA2FAAHPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150381-A2 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2009-12-17 | — | — | WO | disclosed |