SCHEMBL4432034

SCHEMBL4432034

Cc1cc[c]c(-c2cc(C)ccc2Br)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.36
MAOA P21397 2/20 0.36
ELANE P08246 1/20 0.31
ALDH1A1 P00352 3/20 0.30
MAPK1 P28482 1/20 0.30
ALDH2 P05091 1/20 0.30
ALDH3A1 P30838 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4438050 0.89 ALDH1A1 (0.36) MAOBMAOAALDH1A1MAPK1
SCHEMBL4433660 0.86 MAOA (0.33) MAOBMAOAALDH1A1
SCHEMBL4429907 0.82 KIF11 (0.36)
SCHEMBL4553496 0.80 ALDH1A1 (0.39) MAOBMAOAELANEALDH1A1CYP1A2
SCHEMBL4429962 0.77 ALKBH3 (0.36) MAOBMAOAELANEALDH1A1MAPK1
SCHEMBL13407668 0.76 ALDH1A1 (0.43) MAOBMAOAELANEALDH1A1MAPK1
SCHEMBL7049757 0.76 ACHE (0.38) ALDH1A1MAPK1CYP1A2CYP2A6
SCHEMBL10939076 0.76 MAPT (0.39) MAOBMAOAELANEALDH1A1CYP1A2
SCHEMBL4439277 0.74 ALDH1A1 (0.36) ALDH1A1MAPK1
SCHEMBL4429890 0.74 ACHE (0.48) ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121660-A2 FUNGICIDAL AMIDES E. I. Du Pont de Nemours and Company (US) 2009-11-25 EP disclosed
WO-2008091594-A2 FUNGICIDAL MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-31 WO disclosed
WO-2008091580-A2 FUNGICIDAL AMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-31 WO disclosed