Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.59 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.59 |
| ▸ | ITGAL | P20701 | 3/20 | 0.59 |
| ▸ | ACE | P12821 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440562 | 1.00 | ALOX15 (0.61) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL29648934 | 0.85 | OPRM1 (0.62) | — | |
| SCHEMBL30921658 | 0.83 | ITGB2 (0.65) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL3936861 | 0.83 | MCL1 (0.60) | ACEMEN1KMT2A | |
| SCHEMBL24403862 | 0.82 | CCKBR (0.57) | MEN1KMT2A | |
| SCHEMBL28382507 | 0.81 | MCL1 (0.59) | MEN1KMT2A | |
| SCHEMBL28380805 | 0.81 | MCL1 (0.59) | MEN1KMT2A | |
| SCHEMBL22498730 | 0.78 | ITGB2 (0.60) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL30310790 | 0.78 | ITGB2 (0.60) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL31036081 | 0.78 | ITGB2 (0.71) | ALOX15ITGB2ICAM1ITGALACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117536-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | Beiersdorf AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101693-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | BEIERSDORF AG (DE) | 2008-08-28 | — | — | WO | disclosed |