SCHEMBL4433446

SCHEMBL4433446

COP(=O)(OC)Oc1ccc(Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
HPGD P15428 3/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
ALOX15 P16050 1/20 0.49
LMNA P02545 3/20 0.45
NPSR1 Q6W5P4 3/20 0.45
HTT P42858 1/20 0.45
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.42
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
PTGS2 P35354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9549537 0.90 MEN1 (0.52) MEN1KMT2AHPGDCYP3A4TSHR
SCHEMBL1059937 0.86 MEN1 (0.67) MEN1KMT2AHPGDCYP3A4TSHR
SCHEMBL9549528 0.81 MEN1 (0.55) MEN1KMT2AHPGDCYP3A4TSHR
SCHEMBL3292988 0.80 CYP3A4 (0.78) MEN1KMT2AHPGDCYP3A4TSHR
SCHEMBL9462182 0.80 MEN1 (0.59) MEN1KMT2AHPGDCYP3A4TSHR
SCHEMBL5850338 0.80 MEN1 (0.59) MEN1KMT2AHPGDCYP3A4TSHR
SCHEMBL561707 0.80 MEN1 (0.59) MEN1KMT2AHPGDCYP3A4TSHR
SCHEMBL28391672 0.79 CYP3A4 (0.47) MEN1KMT2AHPGDCYP3A4TSHR
SCHEMBL11541949 0.78 HPGD (0.59) MEN1KMT2AHPGDCYP3A4TSHR
SCHEMBL11553341 0.78 HPGD (0.59) MEN1KMT2AHPGDCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015372-A1 Organophosphorous Compounds and Uses Thereof JAL THERAPEUTICS LLC (US) 2026-01-15 US disclosed
EP-2097428-A2 BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Mgp Biotechnologies, Inc. (US) 2009-09-09 EP disclosed
WO-2008055249-A2 BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES MGP BIOTECHNOLOGIES, INC. (US) 2008-05-08 WO disclosed
US-4003966-A Selective phosphorylation process MOBIL OIL CORPORATION (US) 1977-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015372-A1 Organophosphorous Compounds and Uses Thereof ACHE, BCHE, MUSK MEN1 4330/4885KMT2A 3792/4885HPGD 3786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.