Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4433446 | 0.90 | MEN1 (0.57) | MEN1KMT2AHPGDCYP3A4TSHR | |
| SCHEMBL561707 | 0.88 | MEN1 (0.59) | MEN1KMT2AHPGDCYP3A4TSHR | |
| SCHEMBL5850338 | 0.88 | MEN1 (0.59) | MEN1KMT2AHPGDCYP3A4TSHR | |
| SCHEMBL1059937 | 0.81 | MEN1 (0.67) | MEN1KMT2AHPGDCYP3A4TSHR | |
| SCHEMBL4277318 | 0.78 | CYP3A4 (0.50) | HPGDCYP3A4TSHRLMNAALDH1A1 | |
| SCHEMBL9621858 | 0.78 | CYP3A4 (0.50) | HPGDCYP3A4TSHRLMNAALDH1A1 | |
| SCHEMBL4424767 | 0.77 | CA2 (0.60) | MEN1KMT2AHPGDCYP3A4TSHR | |
| SCHEMBL9549528 | 0.76 | MEN1 (0.55) | MEN1KMT2AHPGDCYP3A4TSHR | |
| SCHEMBL9462182 | 0.75 | MEN1 (0.59) | MEN1KMT2AHPGDCYP3A4TSHR | |
| SCHEMBL2776814 | 0.74 | CYP3A4 (0.75) | MEN1KMT2AHPGDCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290583-B1 | $g(a) OLIGONUCLEOTIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1993-04-07 | — | — | EP | disclosed |
| EP-0214908-B1 | COMPOUNDS CONTAINING AN OLIGONUCLEOTIDE SEQUENCE LINKED TO AN INTERCALATING AGENT AND TO AN ACTIVABLE CHEMICAL GROUP, THEIR SYNTHESIS AND APPLICATIONS TO ARTIFICIAL SEQUENCE-SPECIFIC NUCLEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1990-11-07 | — | — | EP | disclosed |
| US-4835263-A | Novel compounds containing an oligonucleotide sequence bonded to an intercalating agent, a process for their synthesis and their use | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1989-05-30 | — | — | US | disclosed |
| EP-0117777-B1 | COMPOUNDS CONTAINING AN OLIGONUCLEOTIDE BONDED TO AN INTERCALLATING AGENT, A PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1987-12-23 | — | — | EP | disclosed |
| EP-0214908-A1 | Compounds containing an oligonucleotide sequence linked to an intercalating agent and to an activable chemical group, their synthesis and applications to artificial sequence-specific nucleases | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1987-03-18 | — | — | EP | disclosed |
| EP-0117777-A1 | Compounds containing an oligonucleotide bonded to an intercallating agent, a process for their preparation and their application | Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1984-09-05 | — | — | EP | disclosed |