Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429012 | 0.81 | RIPK1 (0.37) | ALDH1A1CYP2D6HSD17B10RIPK1HTT | |
| SCHEMBL8612132 | 0.79 | LMNA (0.39) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL27290911 | 0.79 | LMNA (0.39) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL27696592 | 0.79 | KDM4E (0.40) | CYP2C19CYP1A2NPSR1TRPA1 | |
| SCHEMBL6676497 | 0.74 | TAAR1 (0.50) | ALDH1A1CYP2C19KMT2ACHRM2CHRM4 | |
| SCHEMBL7736545 | 0.74 | CYP2C19 (0.41) | ALDH1A1CYP2C19KMT2ACHRM2CHRM4 | |
| SCHEMBL6195799 | 0.73 | RIPK1 (0.43) | ALDH1A1CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL8850805 | 0.73 | CYP2D6 (0.45) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 | |
| SCHEMBL6551716 | 0.73 | KIF11 (0.61) | CYP2D6CYP2C19CHRM2CHRM4CHRM5 | |
| SCHEMBL7306462 | 0.72 | KIF11 (0.36) | ALDH1A1CYP2D6CYP2C19HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023111-B | Modified phenol novolac resin and application thereof | INDSPEC CHEMICAL CORP | 2010-09-29 | — | — | CN | disclosed |
| US-7498371-B2 | Obtained by reacting resorcinol, 2,4-pentanediol, and aldehyde in the presence of an acid catalyst ; relatively low level of free resorcinol; low fuming, lower Mooney viscosity (better processing), better dynamic stiffness properties; used as a methylene acceptor in a vulcanizable rubber; reinforcement | SUMITOMO CHEMICAL CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| CN-101023111-A | Modified phenol novolac resin and application thereof | INDSPEC CHEMICAL CORP (US) | 2007-08-22 | — | — | CN | disclosed |
| EP-1812487-A2 | MODIFIED PHENOLIC NOVOLAK RESINS AND APPLICATIONS THEREOF | INDSPEC CHEMICAL CORPORATION (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006036760-A2 | MODIFIED PHENOLIC NOVOLAK RESINS AND APPLICATIONS THEREOF | INDSPEC CHEMICAL CORPORATION (US) | 2006-04-06 | — | — | WO | disclosed |
| US-20060069191-A1 | Modified phenolic novolak resins and applications thereof | INDSPEC CHEMICAL CORPORATION (US) | 2006-03-30 | — | — | US | disclosed |