Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.49 |
| ▸ | CLK1 | P49759 | 2/20 | 0.49 |
| ▸ | CLK2 | P49760 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | CLK3 | P49761 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574033 | 0.77 | RAB9A (0.49) | GSK3BCLK1CLK2CDK5DYRK1A | |
| SCHEMBL31253099 | 0.70 | GSK3B (0.68) | GSK3BCLK1CLK2CDK5DYRK1A | |
| SCHEMBL23063810 | 0.70 | GSK3B (0.68) | GSK3BCLK1CLK2CDK5DYRK1A | |
| SCHEMBL2192642 | 0.69 | TRPA1 (0.40) | TRPA1ROCK1CTNNB1WNT3ANPC1 | |
| SCHEMBL261380 | 0.68 | CTNNB1 (0.65) | GSK3BCLK1CLK2CDK5DYRK1A | |
| SCHEMBL30270547 | 0.68 | CTNNB1 (0.65) | GSK3BCLK1CLK2CDK5DYRK1A | |
| SCHEMBL17697651 | 0.68 | SLC6A9 (0.51) | NPC1RAB9A | |
| SCHEMBL4039954 | 0.68 | FGFR1 (0.47) | CLK2DYRK1ACLK4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL1665151 | 0.67 | CTNNB1 (0.63) | GSK3BCLK1CLK2CDK5DYRK1A | |
| SCHEMBL27556162 | 0.67 | PTGDR2 (0.54) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094711-A1 | STRUCTURAL MIMETICS OF PROLINE-RICH PEPTIDES AND THE PHARMACEUTICAL USE THEREOF | Forschungsverbund Berlin e.V. (DE) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008040332-A1 | STRUCTURAL MIMETICS OF PROLINE-RICH PEPTIDES AND THE PHARMACEUTICAL USE THEREOF | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2008-04-10 | — | — | WO | disclosed |