Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27334385 | 0.86 | KMT2A (0.67) | KMT2ALMNAHTTMAPTPKM | |
| SCHEMBL1853622 | 0.85 | LMNA (0.71) | KMT2ALMNAHTTMAPTPKM | |
| SCHEMBL18229441 | 0.85 | HRH3 (0.65) | KMT2ALMNAHTTMAPTPKM | |
| SCHEMBL27333849 | 0.83 | LMNA (0.72) | KMT2ALMNAHTTMAPTPKM | |
| SCHEMBL18229463 | 0.82 | KMT2A (0.73) | KMT2ALMNAHTTMAPTGAA | |
| SCHEMBL27334086 | 0.80 | LMNA (0.64) | KMT2ALMNAHTTMAPTPKM | |
| SCHEMBL2402894 | 0.80 | LMNA (0.67) | KMT2ALMNAHTTMAPTPKM | |
| SCHEMBL7976825 | 0.80 | SMN1; SMN2 (0.71) | KMT2ALMNAHTTMAPTPKM | |
| SCHEMBL27337415 | 0.80 | KMT2A (0.69) | KMT2ALMNAHTTMAPTPKM | |
| SCHEMBL23054829 | 0.79 | ALDH1A1 (0.60) | KMT2ALMNAHTTMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134683-A2 | NOVEL INHIBITORS HEPATITIS C VIRUS REPLICATION | Intermune, Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008100867-A2 | NOVEL INHIBITORS HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |