Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | AANAT | Q16613 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | FNTA | P49354 | 1/20 | 0.59 |
| ▸ | FNTB | P49356 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972279 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2GAALMNAALDH1A1AANAT | |
| SCHEMBL1849735 | 0.92 | LMNA (0.65) | SMN1; SMN2GAALMNAALDH1A1AANAT | |
| SCHEMBL10069200 | 0.92 | AANAT (0.77) | LMNAALDH1A1AANATPKMKMT2A | |
| SCHEMBL10272692 | 0.91 | MTNR1A (0.64) | SMN1; SMN2GAALMNAALDH1A1AANAT | |
| SCHEMBL7972207 | 0.91 | LMNA (0.67) | SMN1; SMN2GAALMNAALDH1A1AANAT | |
| SCHEMBL7973953 | 0.90 | GAA (0.60) | SMN1; SMN2GAALMNAALDH1A1AANAT | |
| SCHEMBL7974113 | 0.90 | LMNA (0.62) | SMN1; SMN2GAALMNAALDH1A1AANAT | |
| SCHEMBL7973858 | 0.90 | LMNA (0.62) | SMN1; SMN2GAALMNAALDH1A1AANAT | |
| SCHEMBL6029594 | 0.90 | LMNA (0.62) | SMN1; SMN2GAALMNAALDH1A1AANAT | |
| SCHEMBL7970603 | 0.89 | LMNA (0.61) | SMN1; SMN2GAALMNAALDH1A1AANAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |