Lysine

Lysine

SCHEMBL4435147

NCCCCC(N)C(=O)O.O=C(O)CC(O)C(=O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSR P00390 2/20 0.71
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ ARG2 P78540 4/20 0.46
▸ ARG1 P05089 3/20 0.46
▸ RNPEP Q9H4A4 1/20 0.44
▸ CYP1A2 P05177 3/20 0.44
▸ GRM8 O00222 1/20 0.44
▸ GRM6 O15303 1/20 0.44
▸ GRIN2D O15399 1/20 0.44
▸ GRIN3B O60391 1/20 0.44
▸ GRIK1 P39086 1/20 0.44
▸ GRM5 P41594 1/20 0.44
▸ GRIA1 P42261 1/20 0.44
▸ GRIA2 P42262 1/20 0.44
▸ GRIA3 P42263 1/20 0.44
▸ SLC1A3 P43003 1/20 0.44
▸ SLC1A2 P43004 1/20 0.44
▸ SLC1A1 P43005 1/20 0.44
▸ GRIA4 P48058 1/20 0.44
▸ GRIN1 Q05586 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lysine SCHEMBL3303345 1.00 GSR (0.71) GSRSMN1; SMN2ARG2ARG1RNPEP
Lysine SCHEMBL27946776 0.98 GSR (0.69) GSRSMN1; SMN2ARG2ARG1RNPEP
Lysine SCHEMBL11175666 0.98 GSR (0.69) GSRSMN1; SMN2ARG2ARG1RNPEP
Ornithine SCHEMBL3793499 0.95 GSR (0.62) GSRSMN1; SMN2ARG2ARG1CYP1A2
Ornithine SCHEMBL11171112 0.93 GSR (0.60) GSRSMN1; SMN2ARG2ARG1CYP1A2
Lysine SCHEMBL2589784 0.87 GSR (0.80) GSRARG2ARG1RNPEPCYP1A2
Lysine SCHEMBL31679370 0.87 GSR (0.80) GSRARG2ARG1RNPEPCYP1A2
Lysine SCHEMBL1425215 0.87 GSR (0.80) GSRARG2ARG1RNPEPCYP1A2
Lysine SCHEMBL20952564 0.87 GSR (0.80) GSRARG2ARG1RNPEPCYP1A2
Lysine SCHEMBL18528930 0.87 GSR (0.80) GSRARG2ARG1RNPEPCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115569085-A Supermolecule blue copper peptide solution and preparation method and application thereof 广州熵增科技有限公司 2023-01-06 — — CN claimed
EP-4682242-A1 SOLUTION FOR SUSPENDING CELLS, AND USE OF SAME GAIA BioMedicine Inc. (JP) 2026-01-21 — — EP disclosed
US-20240366673-A1 METHOD FOR TREATING CELLS GAIA BIOMEDICINE INC. (JP) 2024-11-07 — — US disclosed
EP-4400576-A1 METHOD FOR TREATING CELLS GAIA BioMedicine Inc. (JP) 2024-07-17 — — EP disclosed
CN-118103492-A Method for treating cells 盖亚生物制药有限公司 2024-05-28 — — CN disclosed
WO-2023038037-A1 METHOD FOR TREATING CELLS 株式会社ガイアバイオメディシン 2023-03-16 — — WO disclosed
CN-115569085-A Supermolecule blue copper peptide solution and preparation method and application thereof 广州熵增科技有限公司 2023-01-06 — — CN disclosed
CN-115569085-A Supermolecule blue copper peptide solution and preparation method and application thereof 广州熵增科技有限公司 2023-01-06 — — CN disclosed
CN-106884029-A The method of enzyme' s catalysis niacinamide cytimidine dinucleotides 中国科学院大连化学物理研究所 2017-06-23 — — CN disclosed
US-20140323573-A1 METABOLIZABLE SALTS AND USE THEREOF IN DIAGNOSTICS AND THERAPY RÜDINGER, Manfred (DE) 2014-10-30 — — US disclosed
CN-102190589-A Amino acid ionic liquid for foodstuffs and medical treatments INST PROCESS ENG CAS 2011-09-21 — — CN disclosed
EP-2124574-A1 USE OF TERMITE POWDER INOCULUM FOR IMPROVING CULTURE GROWTH Institut de Recherche pour le Développement ( IRD) (FR) 2009-12-02 — — EP disclosed
WO-2008119394-A1 USE OF TERMITE POWDER INOCULUM FOR IMPROVING CULTURE GROWTH INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (I.R.D.) (FR) 2008-10-09 — — WO disclosed
CN-1083266-C Total parenteral nutrition solution containing water-soluble vitamin B TANABE SEIYAKU CO (JP) 2002-04-24 — — CN disclosed
EP-0712583-B1 Total parenteral nutrition solution containing watersoluble vitamin B TANABE SEIYAKU CO (JP) 2001-07-18 — — EP disclosed
WO-1998054351-A1 A COMBINED PROCESS FOR THE PRODUCTION OF LYSINE AND ITS SALTS AND OF A FURTHER WEAK ACID AND A SALT THEREOF AMYLUM BELGIUM N.V. (BE) 1998-12-03 — — WO disclosed
US-5767123-A Total parenteral nutrition solution containing water-soluble vitamin B TANABE SEIYAKU CO., LTD. (JP) 1998-06-16 — — US disclosed
US-5629002-A THIOCYANATES IN SYNERGISTIC COMBINATION WITH ESTROGENS, SULFUR, SULFIDES, VASODILATORS, PROTEIN HYDROLYZATES, AMINO ACIDS, CARBOXYLIC ACIDS, VITAMINS WEUFFEN WOLFGANG (DE) 1997-05-13 — — US disclosed
CN-1129104-A Total parenteral nutrition solution containing water-soluble vitamin B TANABE SEIYAKU CO (JP) 1996-08-21 — — CN disclosed
EP-0712583-A2 Total parenteral nutrition solution containing watersoluble vitamin B TANABE SEIYAKU CO., LTD. (JP) 1996-05-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140323573-A1 METABOLIZABLE SALTS AND USE THEREOF IN DIAGNOSTICS AND THERAPY SLC10A1, BCAT2, BCAT1 GSR 3116/4885SMN1; SMN2 2479/4885ARG2 1819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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