Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.51 |
| ▸ | HTR3B | O95264 | 4/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.51 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | NCF1 | P14598 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19403739 | 0.87 | HTR3A (0.55) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL19385641 | 0.86 | ADRB2 (0.55) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL632018 | 0.84 | HTR3A (0.55) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL630645 | 0.83 | HTR3A (0.54) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL31587131 | 0.82 | HSD11B1 (0.50) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL3216322 | 0.82 | HSD11B1 (0.50) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL14060359 | 0.81 | CDK4 (0.50) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL24681546 | 0.81 | POLB (0.59) | HTR3APHGDHASIC3 | |
| SCHEMBL17115170 | 0.81 | NCF1 (0.48) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL5252902 | 0.81 | MAPT (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716422-B2 | Anionic charge-dynamic polymers for release of cationic agents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-05-06 | — | — | US | disclosed |
| US-8574420-B2 | Ultrathin multilayered films for controlled release of anionic reagents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-11-05 | — | — | US | disclosed |
| US-20130122055-A1 | Anionic Charge-Dynamic Polymers for Release of Cationic Agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-05-16 | — | — | US | disclosed |
| US-8324333-B2 | Anionic charge-dynamic polymers for release of cationic agents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120065616-A1 | Ultrathin Multilayered Films for Controlled Release of Anionic Reagents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-03-15 | — | — | US | disclosed |
| US-20100048736-A1 | ANIONIC CHARGE-DYNAMIC POLYMERS FOR RELEASE OF CATIONIC AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-25 | — | — | US | disclosed |
| US-20090105375-A1 | Ultrathin Multilayered Films for Controlled Release of Anionic Reagents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-04-23 | — | — | US | disclosed |
| WO-2009049100-A2 | ULTRATHIN MULTILAYERED FILMS FOR CONTROLLED RELEASE OF ANIONIC REAGENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130122055-A1 | Anionic Charge-Dynamic Polymers for Release of Cationic Agents | PARG, PARN, CHMP4B | HTR3A 1492/4885HTR3E 888/4885HTR3B 1934/4885 |
| US-20100048736-A1 | ANIONIC CHARGE-DYNAMIC POLYMERS FOR RELEASE OF CATIONIC AGENTS | PARG, PARN, CHMP4B | HTR3A 1492/4885HTR3E 888/4885HTR3B 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.