SCHEMBL707653

SCHEMBL707653

CC(=O)O[SiH2]c1cccc(C)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.41
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TRPA1 O75762 2/20 0.38
ATM Q13315 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
POLB P06746 1/20 0.35
LMNA P02545 3/20 0.35
MAPT P10636 3/20 0.35
RAB9A P51151 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ACHE P22303 1/20 0.34
GAA P10253 2/20 0.34
CYP3A4 P08684 2/20 0.33
MEN1 O00255 1/20 0.33
AKR1B10 O60218 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL707854 0.85 ALDH1A1 (0.38) PTPN1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL10535392 0.84 TRPA1 (0.36) ALDH1A1HSD17B10TRPA1ATMSMN1; SMN2
SCHEMBL7184008 0.83 ALDH1A1 (0.35) PTPN1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL7186486 0.80 TRPA1 (0.33) ALDH1A1HPGDHSD17B10TRPA1ATM
SCHEMBL447683 0.76 TRPA1 (0.41) ALDH1A1TRPA1ATMSMN1; SMN2TSHR
SCHEMBL5409861 0.76 TRPA1 (0.41) ALDH1A1KDM4ETRPA1ATMSMN1; SMN2
SCHEMBL18315768 0.74 TRPA1 (0.39) ALDH1A1TRPA1ATMSMN1; SMN2TSHR
SCHEMBL4435873 0.73 TRPA1 (0.40) ALDH1A1TRPA1ATMSMN1; SMN2TSHR
SCHEMBL1894227 0.72 TRPA1 (0.38) ALDH1A1TRPA1ATMSMN1; SMN2TSHR
SCHEMBL17865460 0.72 MAPT (0.42) ALDH1A1KDM4ETRPA1ATMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4208312-A ACYLOXYSILANE COMPONENT TO EXTEND POT LIFE SHIN-ETSU CHEMICAL CO. LTD. (JP) 1980-06-17 US claimed
EP-3039079-B1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DDP SPECIALTY ELECTRONIC MAT US 9 LLC (US) 2022-05-18 EP disclosed
US-9909007-B2 Curable silicone composition, cured product thereof, and optical semiconductor device DOW CORNING CORPORATION (US) 2018-03-06 US disclosed
EP-2914664-B1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO LTD (JP) 2016-09-07 EP disclosed
US-20160215141-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-07-28 US disclosed
EP-3039079-A1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE Dow Corning Corporation (US) 2016-07-06 EP disclosed
US-9312196-B2 Curable silicone composition, cured product thereof, and optical semiconductor DOW CORNING TORAY CO., LTD. (JP) 2016-04-12 US disclosed
US-20150252220-A1 Curable Silicone Composition, And Semiconductor Sealing Material And Optical Semiconductor Device Using The Same DOW CORNING TORAY CO., LTD. (JP) 2015-09-10 US disclosed
US-20150252221-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor DOW TORAY CO., LTD. (JP) 2015-09-10 US disclosed
EP-2914664-A1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2015-09-09 EP disclosed
EP-2730620-A1 CURABLE SILICON COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2014-05-14 EP disclosed
WO-2014069610-A1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-05-08 WO disclosed
WO-2014046309-A1 CURABLE SILICONE COMPOSITION, AND SEMICONDUCTOR SEALING MATERIAL AND OPTICAL SEMICONDUCTOR DEVICE USING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2014-03-27 WO disclosed
WO-2014002919-A1 COATING AGENT, ELECTRICAL-ELECTRONIC EQUIPMENT, AND METHOD FOR PROTECTING METAL PARTS OF ELECTRICAL-ELECTRONIC EQUIPMENT DOW CORNING TORAY CO., LTD. (JP) 2014-01-03 WO disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20090061633-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-03-05 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed
US-6268440-B1 MIXING WATER BASED COMPOSITE RESINS AND POLYSILOXANES WITH CONDENSATION REACTION, DISPERSION AND DISSOLVING DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-07-31 US disclosed